Hydrochloric Acid

Hydrochloric Acid

SCHEMBL648711

CC1=C(C)C(C)([Zr+2]C2(C)C(C)=C(C)c3ccccc32)c2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3681014 0.76
SCHEMBL4655424 0.74 PGR (0.40)
Hydrochloric Acid SCHEMBL6253955 0.73 ESR1 (0.33)
Hydrochloric Acid SCHEMBL648714 0.72 KDM4E (0.32) GPR35
Hydrochloric Acid SCHEMBL9422126 0.72
Hydrochloric Acid SCHEMBL9422125 0.72
SCHEMBL6350171 0.71 CDC25A (0.33)
Hydrochloric Acid SCHEMBL6129928 0.69 ALDH1A1 (0.32)
SCHEMBL6343281 0.68 GPR35 (0.30) GPR35
SCHEMBL7545664 0.68 NPC1 (0.31) GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1852408-B1 PROCESS FOR THE DIMERIZATION OF ALPHA-OLEFINS IDEMITSU KOSAN CO (JP) 2018-04-04 EP disclosed
US-20130225892-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2013-08-29 US disclosed
US-20120088946-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2012-04-12 US disclosed
US-8119850-B2 Process for producing unsaturated hydrocarbon compound IDEMITSU KOSAN CO., LTD. (JP) 2012-02-21 US disclosed
US-20090069614-A1 METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 US disclosed
US-20090030255-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2009-01-29 US disclosed
EP-1852408-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2007-11-07 EP disclosed
EP-1849757-A1 METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2007-10-31 EP disclosed
US-20010041779-A1 PROCESS FOR MANUFACTURING POLYETHYLENE WITH A FUNCTIONAL END GROUP IN THE PRESENCE OF METALLOCENE CATALYST KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2001-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030255-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND ALOX12, ALOX15B, ALOX15 GPR35 2843/4885
US-20090069614-A1 METHOD FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND AHR, ALOX12, ARNT GPR35 1953/4885
US-20120088946-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND ALOX12, ALOX15B, ALOX15 GPR35 2843/4885
US-20130225892-A1 PROCESS FOR PRODUCING UNSATURATED HYDROCARBON COMPOUND ALOX12, ALOX15B, ALOX15 GPR35 2843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.