Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27037085 | 0.89 | MAPK1 (0.48) | RAB9AL3MBTL1TSHRMAPK1ATM | |
| SCHEMBL6500197 | 0.86 | HTT (0.43) | L3MBTL1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL6502832 | 0.83 | SMN1; SMN2 (0.46) | RAB9AKMT2ATSHRALDH1A1NPC1 | |
| SCHEMBL6501433 | 0.82 | SLC6A2 (0.40) | L3MBTL1CYP17A1ALDH1A1TP53LMNA | |
| SCHEMBL6498870 | 0.82 | ALDH1A1 (0.49) | RAB9AL3MBTL1KMT2AALDH1A1TP53 | |
| SCHEMBL6504970 | 0.79 | CYP19A1 (0.39) | RAB9AL3MBTL1KMT2ANPC1LMNA | |
| SCHEMBL29173275 | 0.77 | L3MBTL1 (0.45) | RAB9AL3MBTL1KMT2ATSHRMAPK1 | |
| SCHEMBL8309987 | 0.76 | LMNA (0.42) | RAB9AL3MBTL1KMT2ATDP1CYP17A1 | |
| SCHEMBL2789136 | 0.76 | LTA4H (0.42) | RAB9AKMT2A | |
| SCHEMBL5184111 | 0.76 | CYP19A1 (0.61) | KMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | RAB9A 958/4885L3MBTL1 4484/4885KMT2A 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.