Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510115 | 0.83 | MAPK14 (0.34) | SLC6A2SLC6A4SLC6A3PTGS2NISCH | |
| SCHEMBL6501378 | 0.82 | RAB9A (0.44) | SLC6A2SLC6A4SLC6A3AURKAPTGS1 | |
| SCHEMBL6510105 | 0.80 | MAPKAPK2 (0.44) | SLC6A2SLC6A4SLC6A3CYP17A1GAA | |
| SCHEMBL3907301 | 0.76 | CYP19A1 (0.41) | SLC6A2SLC6A4SLC6A3MAPTGAA | |
| SCHEMBL3403146 | 0.76 | CYP11B1 (0.41) | SLC6A2SLC6A4SLC6A3CYP17A1 | |
| SCHEMBL2145850 | 0.76 | ALDH1A1 (0.39) | SLC6A2SLC6A4SLC6A3GRK2MAPT | |
| SCHEMBL1515763 | 0.76 | SLC6A3 (0.58) | SLC6A2SLC6A4SLC6A3MAPTLMNA | |
| SCHEMBL6503892 | 0.76 | ROCK2 (0.47) | AURKAALDH1A1 | |
| SCHEMBL7247570 | 0.74 | PTGS2 (0.43) | SLC6A2SLC6A4SLC6A3PTGS2MAPT | |
| SCHEMBL6500197 | 0.73 | HTT (0.43) | AURKALMNATHRBALDH1A1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | SLC6A2 4327/4885SLC6A4 4742/4885SLC6A3 4560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.