SCHEMBL65014

SCHEMBL65014

C=C(C)C(=O)OCC(O)CN(CC(=O)O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
ADRB2 P07550 2/20 0.34
ADRB1 P08588 2/20 0.34
ADRB3 P13945 2/20 0.34
ABCB1 P08183 3/20 0.34
PLA2G2A P14555 1/20 0.33
BLM P54132 1/20 0.33
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2036583 0.90 TSHR (0.38) TSHRLMNATDP1POLBAPEX1
SCHEMBL9145562 0.85 TDP1 (0.36) TSHRLMNATDP1HTTADRB2
SCHEMBL14382215 0.84 TDP1 (0.36) TSHRLMNATDP1POLBAPEX1
SCHEMBL2679520 0.83 GPR174 (0.36) TDP1ABCB1PLA2G2ABLM
SCHEMBL10932059 0.83 TSHR (0.42) TSHRLMNATDP1POLBAPEX1
SCHEMBL17678830 0.81 TSHR (0.39) TSHRLMNATDP1POLBAPEX1
SCHEMBL14409178 0.81 THRB (0.40) TSHRLMNATDP1POLBADRB2
SCHEMBL28559612 0.80 POLB (0.46) TSHRLMNAPOLBABCB1
SCHEMBL22493862 0.79 TSHR (0.33) TSHRLMNATDP1POLBAPEX1
SCHEMBL4102932 0.79 LMNA (0.35) LMNATDP1ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 498 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250017827-A1 Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them IVOCLAR VIVADENT AG (LI) 2025-01-16 US claimed
EP-4488243-A1 ACID-STABLE GLASS FILLERS AND SELF-ADHESIVE DENTAL COMPOSITE CEMENTS CONTAINING SAME HAVING GOOD TRANSPARENCY Ivoclar Vivadent AG (LI) 2025-01-08 EP claimed
US-20240158614-A1 STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY IVOCLAR VIVADENT AG (LI) 2024-05-16 US claimed
EP-4356893-A1 STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY Ivoclar Vivadent AG (LI) 2024-04-24 EP claimed
CN-117917236-A Storage-stable self-adhesive composite cements with good transparency and good radiopacity 义获嘉伟瓦登特公司 2024-04-23 CN claimed
US-20240099942-A1 RADICALLY POLYMERIZABLE COMPOSITION COMPRISING A REDOX INITIATOR SYSTEM BASED ON DIHYDROPYRIDINES IVOCLAR VIVADENT AG (LI) 2024-03-28 US claimed
EP-4331557-A1 RADICALLY POLYMERIZABLE COMPOSITION COMPRISING A REDOX INITIATOR SYSTEM BASED ON DIHYDROPYRIDINES Ivoclar Vivadent AG (LI) 2024-03-06 EP claimed
EP-4205723-A1 HIGH TRANSPARENCY, SULPHATE-CONTAINING OR PHOSPHATE-CONTAINING DENTAL SELF-ADHERING COMPOSITE Ivoclar Vivadent AG (LI) 2023-07-05 EP claimed
EP-4205724-A1 SELF-ADHESIVE DENTAL COMPOSITE CEMENTS WITH GOOD TRANSPARENCY BASED ON ACID-TREATED FILLERS Ivoclar Vivadent AG (LI) 2023-07-05 EP claimed
EP-4205722-A1 SELF-ADHESIVE DENTAL COMPOSITE WITH GOOD TRANSPARENCY Ivoclar Vivadent AG (LI) 2023-07-05 EP claimed
EP-2578201-A1 Dental materials with improved hydrolysis stability on the basis of phthalic acid monomers Ivoclar Vivadent AG (LI) 2013-04-10 EP claimed
WO-2013034778-A2 DENTAL MATERIALS BASED ON COMPOUNDS HAVING DEBONDING-ON-DEMAND PROPERTIES IVOCLAR VIVADENT AG (LI) 2013-03-14 WO claimed
WO-2013034777-A2 DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES IVOCLAR VIVADENT AG (LI) 2013-03-14 WO claimed
EP-2226061-B1 Infiltrant for dental application MUEHLBAUER ERNST GMBH & CO KG (DE) 2012-12-26 EP claimed
EP-2226061-A1 Infiltrant for dental application Ernst Mühlbauer GmbH & Co.KG (DE) 2010-09-08 EP claimed
US-7714034-B2 Photopolymerizable dental materials with bisacylphosphine oxides as initiators IVOCLAR VIVADENT AG (LI) 2010-05-11 US claimed
EP-1749513-B1 Photopolymerisable dental material with bisacylphosphine oxides as initiator IVOCLAR VIVADENT AG (LI) 2009-03-04 EP claimed
EP-1749513-A1 Photopolymerisable dental material with bisacylphosphine oxides as inhibitors Ivoclar Vivadent AG (LI) 2007-02-07 EP claimed
US-20070027229-A1 Photopolymerizable dental materials with bisacylphosphine oxides as initiators IVOCLAR VIVADENT AG (LI) 2007-02-01 US claimed
US-4373035-A Isotonic monomer formulations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1983-02-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240099942-A1 RADICALLY POLYMERIZABLE COMPOSITION COMPRISING A REDOX INITIATOR SYSTEM BASED ON DIHYDROPYRIDINES TAS1R1, TAS2R1, TAS2R41 TSHR 4092/4885LMNA 3743/4885TDP1 89/4885
US-20250017827-A1 Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them HAO2, HAO1, CDH1 TSHR 4061/4885LMNA 2791/4885TDP1 3608/4885
US-20070027229-A1 Photopolymerizable dental materials with bisacylphosphine oxides as initiators PRXL2A, PGM2, PAM TSHR 1818/4885LMNA 913/4885TDP1 2404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.