Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506073 | 0.92 | LMNA (0.44) | DRD2DRD3USP2LMNAGLA | |
| SCHEMBL6500166 | 0.92 | HTR1A (0.43) | DRD2DRD3USP2LMNAGLA | |
| SCHEMBL6502583 | 0.91 | LMNA (0.48) | DRD2DRD3LMNATSHRALDH1A1 | |
| SCHEMBL6500224 | 0.91 | ALDH1A1 (0.50) | DRD2DRD3USP2LMNATSHR | |
| SCHEMBL6509242 | 0.88 | MAOB (0.54) | LMNATSHRKMT2AMEN1MAPT | |
| SCHEMBL6501982 | 0.87 | DRD2 (0.47) | DRD2DRD3USP2LMNAGLA | |
| Hydrochloric Acid SCHEMBL6504357 | 0.87 | MAOB (0.53) | LMNATSHRKMT2AMEN1MAPT | |
| SCHEMBL6500880 | 0.87 | LMNA (0.51) | DRD2DRD3LMNATSHRMAPK1 | |
| SCHEMBL6510748 | 0.87 | HTR6 (0.46) | DRD2DRD3MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL6504564 | 0.86 | HTR6 (0.54) | DRD2DRD3LMNATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |