Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ATP4A | P20648 | 10/20 | 0.49 |
| ▸ | ATP4B | P51164 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508538 | 0.84 | RAB9A (0.74) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL6507381 | 0.82 | RAB9A (0.54) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL6515410 | 0.76 | ADORA2A (0.56) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL5923152 | 0.74 | PHGDH (0.46) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL6509589 | 0.74 | RAB9A (0.63) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL6510261 | 0.72 | LMNA (0.52) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL6515320 | 0.71 | SIGMAR1 (0.46) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL5923420 | 0.70 | SMN1; SMN2 (0.52) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL6507985 | 0.69 | NPC1 (0.47) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 | |
| SCHEMBL6506989 | 0.68 | CRHBP (0.70) | KMT2ASMN1; SMN2MEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |