SCHEMBL6513405

SCHEMBL6513405

C=C(C)C[SiH](Cl)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 1/20 0.33
HIF1A Q16665 1/20 0.33
EGFR P00533 2/20 0.32
LMNA P02545 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1316781 0.72 NOS2 (0.37) ALDH1A1MEN1GAAMAPTALOX15
SCHEMBL2272014 0.70 TP53 (0.38) ALDH1A1HIF1ALMNA
SCHEMBL2102293 0.70 KDM4E (0.38) MEN1MAPTKMT2ALMNAKDM4E
SCHEMBL2272064 0.67 TP53 (0.35)
SCHEMBL2100218 0.67 HTT (0.33) GAA
SCHEMBL27176122 0.67 GPR174 (0.39) ALDH1A1MEN1GAAMAPTALOX15
SCHEMBL27290628 0.66 LOXL2 (0.38) ALDH1A1MEN1ALOX15KMT2AKDM4E
SCHEMBL7052676 0.65 RIPK1 (0.32) ALDH1A1MEN1GAAKMT2ALMNA
SCHEMBL2100800 0.65 ALDH1A1 (0.39) ALDH1A1MAPTHIF1ALMNA
SCHEMBL9702347 0.65 MAOA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050124747-A1 Coating composition for ink-jet recording medium and ink-jet recording medium DEUTSCHE BANK AG, NEW YORK BRANCH, AS COLLATERAL AGENT 2005-06-09 US disclosed
EP-1470928-A1 COATING COMPOSITION FOR INK-JET RECORDING MEDIUM AND INK-JET RECORDING MEDIUM Clariant International Ltd. (CH) 2004-10-27 EP disclosed
EP-1114734-A1 RESIN COMPOSITION FOR INK-JET RECORDING SHEET AND RECORDING SHEET MADE WITH THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-07-11 EP disclosed
EP-0989162-A1 THERMOPLASTIC RESIN COMPOSITION, WATER-BASED COMPOSITION, HEAT-SENSITIVE PRESSURE-SENSITIVE ADHESIVE, AND HEAT-SENSITIVE SHEET Daicel Chemical Industries, Ltd. (JP) 2000-03-29 EP disclosed
EP-0989168-A1 Water-based coating composition Daicel Chemical Industries, Ltd. (JP) 2000-03-29 EP disclosed