Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668046 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL652060 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL17789983 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL4863944 | 0.80 | THRB (0.52) | ALDH1A1TSHRHTTTDP1 | |
| SCHEMBL13120306 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL330791 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL6362567 | 0.79 | TSHR (0.30) | TSHR | |
| SCHEMBL11021303 | 0.78 | LMNA (0.37) | LMNA | |
| SCHEMBL1174610 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL9150298 | 0.78 | ALDH1A1 (0.63) | ALDH1A1TSHRCHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119667-B2 | Carbonates of fenicol antibiotics | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-8084643-B2 | Nitrogen-containing esters of the secondary alcohol group of florfenicol and of its analogs,including salts; veterinary medicine; nonhydrolyzing as needed to maintain the prodrug in aqueous solution in the subjects system until appropriate; cattle drinking water; bovine respiratory disease | INTERVET INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-8044230-B2 | Hydrolytic stability needed to maintain the prodrug in solution in the subject's system until appropriate conditions exist when the prodrug can hydrolyze, releasing the active compound | INTERVET INC. (US) | 2011-10-25 | — | — | US | disclosed |
| EP-1966129-B1 | CARBONATES OF FENICOL ANTIBIOTICS | SCHERING PLOUGH LTD (CH) | 2011-08-17 | — | — | EP | disclosed |
| EP-2102154-A1 | WATER-SOLUBLE PRODRUGS OF CHLORAMPHENICOL, THIAMPHENICOL, AND ANALOGS THEREOF | Schering-Plough Ltd. (CH) | 2009-09-23 | — | — | EP | disclosed |
| EP-2101750-A2 | WATER-SOLUBLE PHENICOL PRODRUGS IN A LIPOPHILIC VEHICLE SYSTEM | Schering-Plough Ltd. (CH) | 2009-09-23 | — | — | EP | disclosed |
| EP-2091909-A1 | WATER-SOLUBLE PRODRUGS OF FLORFENICOL AND ITS ANALOGS | Schering-Plough Ltd. (CH) | 2009-08-26 | — | — | EP | disclosed |
| EP-1966129-A2 | CARBONATES OF FENICOL ANTIBIOTICS | Schering-Plough Ltd. (CH) | 2008-09-10 | — | — | EP | disclosed |
| US-20080188556-A1 | Water-Soluble Prodrugs of Florfenicol and its Analogs | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2008-08-07 | — | — | US | disclosed |
| WO-2008076259-A1 | WATER-SOLUBLE PRODRUGS OF FLORFENICOL AND ITS ANALOGS | SCHERING-PLOUGH LTD. (CH) | 2008-06-26 | — | — | WO | disclosed |
| US-20080153906-A1 | Water-Soluble Phenicol Prodrugs in a Lipophilic Vehicle System | INTERVET INC. | 2008-06-26 | — | — | US | disclosed |
| WO-2008076256-A1 | WATER-SOLUBLE PRODRUGS OF CHLORAMPHENICOL, THIAMPHENICOL, AND ANALOGS THEREOF | SCHERING-PLOUGH LTD. (CH) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008076261-A2 | WATER-SOLUBLE PHENICOL PRODRUGS IN A LIPOPHILIC VEHICLE SYSTEM | SCHERING-PLOUGH LTD. (CH) | 2008-06-26 | — | — | WO | disclosed |
| US-20080146640-A1 | Water-Soluble Prodrugs of Chloramphenicol, Thiamphenicol, and Analogs Thereof | SCHERING-PLOUGH LTD. (CH) | 2008-06-19 | — | — | US | disclosed |
| WO-2007079010-A2 | CARBONATES OF FENICOL ANTIBIOTICS | SCHERING-PLOUGH LTD. (CH) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155799-A1 | CARBONATES OF FENICOL ANTIBIOTICS | INTERVET INC. | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153906-A1 | Water-Soluble Phenicol Prodrugs in a Lipophilic Vehicle System | BPHL, CYP4B1, CYP4A22 | ALDH1A1 787/4885TSHR 2907/4885CHRM5 239/4885 |
| US-20070155799-A1 | CARBONATES OF FENICOL ANTIBIOTICS | CYP4F3, TET1, CYP4F2 | ALDH1A1 3459/4885TSHR 3125/4885CHRM5 2286/4885 |
| US-20080188556-A1 | Water-Soluble Prodrugs of Florfenicol and its Analogs | PFAS, ADH5, SI | ALDH1A1 312/4885TSHR 3559/4885CHRM5 2311/4885 |
| US-20080146640-A1 | Water-Soluble Prodrugs of Chloramphenicol, Thiamphenicol, and Analogs Thereof | TREH, ADH5, CES2 | ALDH1A1 11/4885TSHR 1911/4885CHRM5 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.