Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504727 | 0.83 | S1PR1 (0.45) | S1PR2S1PR1MMP12S1PR4S1PR3 | |
| SCHEMBL6527017 | 0.79 | MMP12 (0.40) | S1PR2S1PR1MMP12S1PR4S1PR3 | |
| SCHEMBL6530514 | 0.77 | FDFT1 (0.41) | MMP12 | |
| SCHEMBL6529355 | 0.76 | S1PR1 (0.35) | S1PR2S1PR1S1PR4S1PR3 | |
| SCHEMBL6527581 | 0.76 | MMP12 (0.36) | S1PR2S1PR1MMP12LTA4H | |
| SCHEMBL6530174 | 0.75 | LMNA (0.39) | S1PR2S1PR1S1PR4S1PR3 | |
| SCHEMBL6529512 | 0.75 | MMP12 (0.40) | MMP12 | |
| SCHEMBL6532172 | 0.75 | LTA4H (0.42) | LTA4H | |
| SCHEMBL6530992 | 0.74 | LMNA (0.40) | MMP12 | |
| SCHEMBL6530119 | 0.74 | S1PR1 (0.44) | S1PR1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |