Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.44 |
| ▸ | HTR3B | O95264 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 3/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474864 | 0.75 | SLC16A3 (0.49) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL2302994 | 0.75 | ITGB3 (0.61) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Trifluoroacetic Acid SCHEMBL30355108 | 0.74 | HTR3E (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6607017 | 0.73 | HTR6 (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27771950 | 0.73 | HTR3E (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Propionic Acid SCHEMBL6610077 | 0.73 | ALDH1A1 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27898242 | 0.72 | ESRRG (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL23010850 | 0.72 | ADRB1 (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5637951 | 0.72 | DAO (0.49) | ALDH1A1TSHRHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL16240933 | 0.72 | EGFR (0.52) | ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337528-B1 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | VITA LAB (ES) | 2004-08-04 | — | — | EP | disclosed |
| US-20040034219-A1 | Benzothiophene derivative compounds process of preparation and use thereof | LABORATORIOS VITA, S.A. (ES) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034219-A1 | Benzothiophene derivative compounds process of preparation and use thereof | TPH1, HTR1A, HTR5A | HTR3E 19/4885HTR3B 8/4885HTR3A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.