Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580557 | 0.86 | HTR3E (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29979524 | 0.86 | HTR3E (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Tert-Butyl Formate SCHEMBL28781853 | 0.77 | HTR1A (0.44) | MAPTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1225685 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL1537900 | 0.75 | HTR3E (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5382950 | 0.75 | TERT (0.53) | ALDH1A1MAPTKDM4EHSD17B10ENPP2 | |
| SCHEMBL3342144 | 0.73 | TERT (0.52) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| Propionic Acid SCHEMBL6598879 | 0.73 | ENPP2 (0.51) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| Propionic Acid SCHEMBL6607026 | 0.73 | ADRB1 (0.74) | MAPTADRB1HTR1AHTR6HTR2A | |
| SCHEMBL6610074 | 0.73 | HTR3E (0.44) | ALDH1A1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337528-B1 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | VITA LAB (ES) | 2004-08-04 | — | — | EP | disclosed |
| US-20040034219-A1 | Benzothiophene derivative compounds process of preparation and use thereof | LABORATORIOS VITA, S.A. (ES) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034219-A1 | Benzothiophene derivative compounds process of preparation and use thereof | TPH1, HTR1A, HTR5A | ALDH1A1 414/4885MAPT 157/4885KDM4E 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.