Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28539062 | 0.80 | POLB (0.32) | POLBDPP4 | |
| SCHEMBL5518522 | 0.79 | ALDH1A1 (0.32) | POLB | |
| SCHEMBL8570280 | 0.79 | POLB (0.34) | POLBDPP4 | |
| SCHEMBL23869968 | 0.73 | POLB (0.31) | POLB | |
| SCHEMBL26700648 | 0.73 | POLB (0.31) | POLB | |
| SCHEMBL16000128 | 0.72 | CHRM2 (0.50) | — | |
| SCHEMBL613970 | 0.71 | RIPK1 (0.42) | — | |
| SCHEMBL22809834 | 0.71 | POLB (0.30) | POLB | |
| SCHEMBL23370118 | 0.71 | AOC2 (0.35) | POLB | |
| SCHEMBL5512354 | 0.71 | FAAH (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166583-A1 | ESTER ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| US-20170166583-A1 | ESTER ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| US-20170166582-A1 | PYRAZOLE ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| US-20170166582-A1 | PYRAZOLE ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| US-7176205-B2 | Bi-pyridinyl derivatives as NK-1 antagonists | HOFFMANN-LA ROCHE INC. (US) | 2007-02-13 | — | — | US | disclosed |
| EP-1182191-B1 | Method for making amides | INT FLAVORS & FRAGRANCES INC (US) | 2004-07-14 | — | — | EP | disclosed |
| US-6437183-B1 | REACTING NITRILE COMPOUNDS WITH SULFATE COMPOUNDS IN DIOL OR TRIOL SOLVENT | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-08-20 | — | — | US | disclosed |
| US-20020028969-A1 | Method for making amides | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-07 | — | — | US | disclosed |
| EP-1182191-A1 | Method for making amides | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2002-02-27 | — | — | EP | disclosed |
| US-6303817-B1 | MORE SPECIFICALLY A METHOD OF MAKING BUTANAMIDES IN A NEW PROCESS; REACTION OF NITRILE COMPOUNDS AND A SULFATE COMPOUND | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2001-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166583-A1 | ESTER ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT2 | POLB 1465/4885DPP4 558/4885 |
| US-20020028969-A1 | Method for making amides | NAAA, NIT2, SULT2A1 | POLB 2923/4885DPP4 1639/4885 |
| US-20170166582-A1 | PYRAZOLE ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, PC | POLB 1536/4885DPP4 829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.