Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659951 | 0.86 | MAPT (0.40) | MAOBMAOAMAPTNPC1RAB9A | |
| SCHEMBL6657970 | 0.81 | ACHE (0.39) | ACHEMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL6657367 | 0.81 | HTR6 (0.42) | ACHEALDH1A1MEN1KMT2A | |
| SCHEMBL6660658 | 0.80 | CHRNB4 (0.43) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6658483 | 0.80 | MAPT (0.45) | ACHEMAPTALDH1A1MEN1MAPK1 | |
| SCHEMBL6658785 | 0.79 | CHRNB4 (0.44) | — | |
| SCHEMBL6660137 | 0.78 | CYP2D6 (0.42) | MAPTNPC1ALDH1A1RAB9AMAPK1 | |
| SCHEMBL6661589 | 0.78 | LTA4H (0.41) | ACHEMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL6657190 | 0.77 | KCNH2 (0.42) | MAPTMEN1KMT2A | |
| SCHEMBL6657776 | 0.77 | MAOB (0.48) | MAOBMAOAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |