Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PAM | P19021 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14421969 | 0.98 | DGKA (0.61) | DGKALMNAMAPTPAMCES2 | |
| SCHEMBL2184258 | 0.98 | DGKA (0.61) | DGKALMNAMAPTPAMCES2 | |
| SCHEMBL2181366 | 0.98 | DGKA (0.61) | DGKALMNAMAPTPAMCES2 | |
| SCHEMBL1401720 | 0.98 | DGKA (0.61) | DGKALMNAMAPTPAMCES2 | |
| SCHEMBL2182481 | 0.98 | DGKA (0.61) | DGKALMNAMAPTPAMCES2 | |
| SCHEMBL27469025 | 0.95 | DGKA (0.59) | DGKALMNAMAPTPAMCES2 | |
| SCHEMBL5139559 | 0.95 | — | — | |
| SCHEMBL19358157 | 0.93 | DGKA (0.57) | DGKALMNAMAPTPAMCES2 | |
| SCHEMBL5050853 | 0.88 | — | — | |
| SCHEMBL2234093 | 0.86 | TERT (0.61) | LMNAMAPTPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021054927-A2 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2021-03-25 | — | — | WO | claimed |
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2020-02-13 | — | — | US | claimed |
| US-9622969-B2 | Polymer conjugated protein micelles | SOUTH DAKOTA STATE UNIV (US) | 2017-04-18 | — | — | US | claimed |
| US-20140370110-A1 | POLYMER CONJUGATED PROTEIN MICELLES | SOUTH DAKOTA STATE UNIVERSITY (US) | 2014-12-18 | — | — | US | claimed |
| EP-2214716-B1 | HYDROXYAPATITE-TARGETING MULTIARM POLYMERS AND CONJUGATES MADE THEREFROM | NEKTAR THERAPEUTICS (US) | 2021-11-17 | — | — | EP | disclosed |
| WO-2021054927-A2 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2021-03-25 | — | — | WO | disclosed |
| US-10668161-B2 | Therapeutic hyperbranched polyglycerol encapsulated biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-06-02 | — | — | US | disclosed |
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2020-02-13 | — | — | US | disclosed |
| CN-109562137-A | Methods and compositions for treating conditions associated with abnormal inflammatory responses | 第波生物公司 | 2019-04-02 | — | — | CN | disclosed |
| US-20190021999-A1 | EXTREMELY SMALL NANOPARTICLES OF DEGRADABLE POLYMERS | PHOSPHOREX, INC. | 2019-01-24 | — | — | US | disclosed |
| EP-3337455-A1 | EXTREMELY SMALL NANOPARTICLES OF DEGRADABLE POLYMERS | Phosphorex Inc. (US) | 2018-06-27 | — | — | EP | disclosed |
| EP-2319542-B1 | Segmented degradable polymers and conjugates made therefrom | NEKTAR THERAPEUTICS (US) | 2018-03-21 | — | — | EP | disclosed |
| US-6419017-B1 | REACTING GROUP 2A COMPOUND, FATTY ACID; PRECIPITATION | BJ SERVICES COMPANY | 2002-07-16 | — | — | US | disclosed |
| US-6365146-B1 | POLYAMIDEESTER COPOLYMER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2002-04-02 | — | — | US | disclosed |
| WO-2002025055-A1 | METHOD OF PREVENTING GAS BREAKTHROUGH IN AN OIL BEARING FORMATION | BJ SERVICES COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |
| US-20020035217-A1 | Hyperbranched polymeric micelles for encapsulation and delivery of hydrophobic molecules | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2002-03-21 | — | — | US | disclosed |
| EP-1176983-A2 | HYPERBRANCHED POLYMERIC MICELLES FOR ENCAPSULATION AND DELIVERY OF HYDROPHOBIC MOLECULES | RUTGERS, THE STATE UNIVERSITY (US) | 2002-02-06 | — | — | EP | disclosed |
| US-6328988-B1 | DRUGS AND COSMETICS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2001-12-11 | — | — | US | disclosed |
| CN-1291898-A | Remedies for corneal epithelium disturbance | WAKAMOTO PHARMA CO LTD (JP) | 2001-04-18 | — | — | CN | disclosed |
| WO-2000065024-A2 | HYPERBRANCHED POLYMERIC MICELLES FOR ENCAPSULATION AND DELIVERY OF HYDROPHOBIC MOLECULES | RUTGERS, THE STATE UNIVERSITY (US) | 2000-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10668161-B2 | Therapeutic hyperbranched polyglycerol encapsulated biomolecules | FABP2, SI, PNLIP | DGKA 950/4885LMNA 2893/4885MAPT 2555/4885 |
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | GSTK1, GSTO1, GSTM2 | DGKA 126/4885LMNA 3751/4885MAPT 1050/4885 |
| US-20140370110-A1 | POLYMER CONJUGATED PROTEIN MICELLES | MTDH, PSMG3, GHITM | DGKA 3620/4885LMNA 1032/4885MAPT 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.