SCHEMBL668752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL668793	0.83	HTT (0.54)	CTSDRXFP1CA12CA1CA2
	SCHEMBL14864224	0.83	LMNA (0.53)	CTSDRXFP1CA12CA1CA2
	SCHEMBL28663786	0.81	KDM4E (0.42)	CTSDCA12CA1CA2CA7
	SCHEMBL668753	0.81	HTT (0.53)	CTSDRXFP1CA12CA1CA2
	SCHEMBL2514158	0.78	CTSD (0.56)	CTSDRXFP1NPC1HTTSMN1; SMN2
	SCHEMBL505777	0.78	CA1 (0.50)	CA12CA1CA2CA7CA9
	SCHEMBL6689608	0.77	NPC1 (0.51)	NPC1HTTLMNASMN1; SMN2HPGD
	SCHEMBL730839	0.77	KDM4E (0.53)	CTSDCA12CA1CA2CA7
	SCHEMBL28837855	0.77	CA12 (0.46)	CTSDCA12CA1CA2CA7
	SCHEMBL19272171	0.75	CA12 (0.41)	CTSDRXFP1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.