Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 4/20 | 0.48 |
| ▸ | CA4 known ✓ | P22748 | 4/20 | 0.46 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.46 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902802 | 0.87 | CA4 (0.50) | CA4CA1BBOX1FFAR3HDAC3 | |
| Succinic Acid SCHEMBL30445005 | 0.85 | LMNA (0.44) | CA12CA6CA7CA9CA14 | |
| SCHEMBL1305256 | 0.83 | MAOA (0.45) | CA12CA6CA7CA9CA14 | |
| SCHEMBL356866 | 0.83 | — | — | |
| Valeric Acid SCHEMBL4580466 | 0.83 | CA1 (0.68) | CA2CA1FFAR3HDAC3HDAC1 | |
| SCHEMBL7576806 | 0.83 | PAOX (0.53) | CA12CA6CA7CA9CA14 | |
| Ethylenediamine SCHEMBL8853631 | 0.81 | MAOA (0.43) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL155357 | 0.80 | CA12 (0.53) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL29259811 | 0.80 | CA12 (0.53) | CA12CA6CA7CA9CA14 | |
| Acetic Acid SCHEMBL9568670 | 0.80 | CA12 (0.53) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897424-A | Aqueous polyurethane urea dispersions | 科思创德国股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117756159-A | Method for preparing layered calcium sulfate by using phosphogypsum | 贵州省材料产业技术研究院 | 2024-03-26 | — | — | CN | claimed |
| CN-117510356-A | Formaldehyde-removing compound, preparation method thereof and application thereof in preparation of formaldehyde-removing aqueous polyurethane dispersion | 万华化学集团股份有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-115746252-A | Aqueous polyurethane urea dispersions | 科思创德国股份有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-115058000-A | Flame-retardant polyester diol and flame-retardant waterborne polyurethane | 江苏景宏新材料科技有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-113072832-A | Combined rheology modifier and preparation method and application thereof | 万华化学集团股份有限公司 | 2021-07-06 | — | — | CN | claimed |
| CN-122094997-A | Aqueous polyurethane coatings for printing applications | — | 2026-05-26 | — | — | CN | disclosed |
| EP-4634252-A1 | AQUEOUS COMPOSITIONS COMPRISING (METH)ACRYLATE GROUP CARRYING POLYURETHANE WHICH YIELD CROSS-LINKED LAYERS OF HIGH HARDNESS AND GOOD ADHESION | BASF SE (DE) | 2025-10-22 | — | — | EP | disclosed |
| US-20250145756-A1 | RE-DISPERSIBLE OR RE-SOLUBLE AQUEOUS ETHYLENICALLY UNSATURATED AQUEOUS POLYURETHANE COMPOSITIONS WITH IMPROVED WATER-RESISTANCE | BASF SE (DE) | 2025-05-08 | — | — | US | disclosed |
| EP-4493608-A1 | RE-DISPERSIBLE OR RE-SOLUBLE AQUEOUS ETHYLENICALLY UNSATURATED AQUEOUS POLYURETHANE COMPOSITIONS WITH IMPROVED WATER-RESISTANCE | BASF SE (DE) | 2025-01-22 | — | — | EP | disclosed |
| WO-2024126304-A1 | AQUEOUS COMPOSITIONS COMPRISING (METH)ACRYLATE GROUP CARRYING POLYURETHANE WHICH YIELD CROSS-LINKED LAYERS OF HIGH HARDNESS AND GOOD ADHESION | BASF SE (DE) | 2024-06-20 | — | — | WO | disclosed |
| EP-3887422-B1 | PROCESS TO PREPARE AQUEOUS POLYURETHANE DISPERSIONS THAT ARE SUBSTANTIALLY FREE OF VOLATILE ORGANIC COMPOUNDS AND THAT HAVE A HIGH SOLIDS CONTENT | STAHL INT B V (NL) | 2024-06-05 | — | — | EP | disclosed |
| CN-117897424-A | Aqueous polyurethane urea dispersions | 科思创德国股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2016202654-A1 | WATER-BASED PRINTING INK COMPRISING AN AQUEOUS DISPERSED POLYURETHANE BINDER AND AN AQUEOUS DISPERSED POLY(METH)ACRYLATE BINDER | BASF SE (DE) | 2016-12-22 | — | — | WO | disclosed |
| US-9404020-B2 | Aqueous blocked polyurethane-urea dispersion | COVESTRO DEUTSCHLAND AG (DE) | 2016-08-02 | — | — | US | disclosed |
| US-20150141573-A1 | AQUEOUS BLOCKED POLYURETHANE-UREA DISPERSION | COVESTRO DEUTSCHLAND AG (DE) | 2015-05-21 | — | — | US | disclosed |
| US-20130095330-A1 | PROCESS FOR THE PREPARATION OF LOW-VISCOSITY, WATER-DILUTABLE URETHANE (METH)ACRYLATES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-18 | — | — | US | disclosed |
| US-20040245490-A1 | Top coating composition for leather | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-09 | — | — | US | disclosed |
| US-20030198796-A1 | Stabilized aqueous crosslinker dispersions | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | disclosed |
| US-5470899-A | With ester | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-28 | — | — | US | disclosed |