Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.46 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 5/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701726 | 0.85 | USP28 (0.49) | MAOBMAOAUSP28USP25SLC6A4 | |
| SCHEMBL6696303 | 0.84 | USP28 (0.54) | MAOBMAOAUSP28USP25SLC6A4 | |
| SCHEMBL6699769 | 0.81 | USP28 (0.47) | MAOBMAOAUSP28USP25SLC6A4 | |
| SCHEMBL18931735 | 0.76 | GPR3 (0.38) | MAOBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6700864 | 0.75 | RXRA (0.51) | MAOBMAOAUSP28USP25PTGER1 | |
| SCHEMBL1668610 | 0.75 | CCR5 (0.58) | USP28USP25SLC6A4CCR5PTGER1 | |
| SCHEMBL2349915 | 0.73 | PTPRZ1 (0.46) | MAOBAPPMRGPRX4AR | |
| SCHEMBL6700568 | 0.72 | MAOB (0.48) | MAOBMAOAUSP28USP25CCR5 | |
| SCHEMBL2889904 | 0.72 | MAOB (0.42) | MAOBMAOACCR5SMN1; SMN2XDH | |
| SCHEMBL24133953 | 0.71 | GPR3 (0.39) | MAOBSLC6A4MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176446-A1 | Substituted amino dicarboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176446-A1 | Substituted amino dicarboxylic acid derivatives | BCAT2, BCAT1, AADAT | MAOB 2990/4885MAOA 2728/4885USP28 3552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.