Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 10/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709012 | 0.90 | ABL1 (0.45) | ABL1THRBTRPV1MEN1GALK1 | |
| SCHEMBL6710123 | 0.90 | ABL1 (0.43) | ABL1THRBTRPV1MEN1GALK1 | |
| SCHEMBL6710151 | 0.86 | ROCK2 (0.40) | ABL1TDP2THRBITKTRPV1 | |
| SCHEMBL6710082 | 0.85 | ROCK2 (0.37) | THRBROCK2 | |
| SCHEMBL6707687 | 0.84 | PYGM (0.39) | ABL1THRBMEN1KMT2AROCK2 | |
| SCHEMBL6710026 | 0.84 | ROCK2 (0.41) | MEN1KMT2AMAPTROCK2 | |
| SCHEMBL6707688 | 0.83 | ADORA2B (0.38) | THRBROCK2 | |
| SCHEMBL6709892 | 0.82 | RAB9A (0.41) | MEN1KMT2AMAPTROCK2 | |
| SCHEMBL6713177 | 0.82 | NAMPT (0.39) | THRBROCK2 | |
| SCHEMBL6713409 | 0.82 | TDP2 (0.42) | TDP2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ABL1 344/4885TDP2 3788/4885THRB 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.