SCHEMBL671509

SCHEMBL671509

CCOC(=O)NN1C(=O)CCC1=O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.48
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
GAA P10253 7/20 0.38
ALDH1A1 P00352 6/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP3A4 P08684 1/20 0.38
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15528690 0.81 KDM4E (0.42) KDM4EKMT2AGAAALDH1A1SMN1; SMN2
SCHEMBL9390898 0.79 KDM4E (0.37) KDM4E
SCHEMBL5069095 0.77 GSK3A (0.50) KDM4EKMT2ANFKB1NFKB2RELA
SCHEMBL13182184 0.74 KDM4E (0.44) KDM4EKMT2AMEN1GAAALDH1A1
SCHEMBL19959701 0.73 NFKB1 (0.40) KDM4EKMT2AMEN1NFKB1NFKB2
SCHEMBL10908440 0.73 ALDH1A1 (0.42) KDM4EKMT2AMEN1GAAALDH1A1
SCHEMBL4132084 0.72 KDM4E (0.36) KDM4E
SCHEMBL1162244 0.72 KDM4E (0.38) KDM4EGAAALDH1A1SMN1; SMN2
SCHEMBL7590942 0.72 KDM4E (0.57) KDM4EKMT2AMEN1GAAALDH1A1
SCHEMBL9066916 0.72 JUN (0.49) NFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4337673-B1 PSD-95 INHIBITORS AND USES THEREOF UNIV COPENHAGEN (DK) 2025-07-09 EP disclosed
US-20250215052-A1 INHIBITORS OF PICK1 AND USES THEREOF UNIVERSITY OF COPENHAGEN (DK) 2025-07-03 US disclosed
US-20240245793-A1 PSD-95 INHIBITORS AND USES THEREOF UNIVERSITY OF COPENHAGEN (DK) 2024-07-25 US disclosed
EP-4337673-A1 PSD-95 INHIBITORS AND USES THEREOF University of Copenhagen (DK) 2024-03-20 EP disclosed
CN-117295755-A PSD-95 inhibitor and application thereof 哥本哈根大学 2023-12-26 CN disclosed
CN-116940594-A Compositions, kits and methods useful for analyzing samples containing antibodies 沃特世科技公司 2023-10-24 CN disclosed
WO-2022238530-A1 PSD-95 INHIBITORS AND USES THEREOF UNIVERSITY OF COPENHAGEN (DK) 2022-11-17 WO disclosed
US-20210347821-A1 INHIBITORS OF PICK1 AND USES THEREOF UNIVERSITY OF COPENHAGEN (DK) 2021-11-11 US disclosed
US-9902754-B2 Modified peptides as potent inhibitors of the PSD-95/NMDA receptor interaction UNIVERSITY OF COPENHAGEN (DK) 2018-02-27 US disclosed
US-20160176924-A1 MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION UNIVERSITY OF COPENHAGEN (DK) 2016-06-23 US disclosed
EP-2320927-A2 MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION University of Copenhagen (DK) 2011-05-18 EP disclosed
WO-2010004003-A2 MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION UNIVERSITY OF COPENHAGEN (DK) 2010-01-14 WO disclosed
US-20090285780-A1 PEG LINKER COMPOUNDS AND BIOLOGICALLY ACTIVE CONJUGATES THEREOF LEE CHYI 2009-11-19 US disclosed
EP-2089052-A1 PEG LINKER COMPOUNDS AND BIOLOGICALLY ACTIVE CONJUGATES THEREOF Peg Biosciences (US) 2009-08-19 EP disclosed
WO-2007140282-A1 PEG LINKER COMPOUNDS AND BIOLOGICALLY ACTIVE CONJUGATES THEREOF PEG BIOSCIENCES (US) 2007-12-06 WO disclosed
EP-0399184-B1 Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay ABBOTT LAB (US) 1995-09-13 EP disclosed
US-5354693-A Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassy ABBOTT LABORATORIES (US) 1994-10-11 US disclosed
US-5248791-A Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay ABBOTT LABORATORIES (US) 1993-09-28 US disclosed
US-5101015-A Nitrogen-functional-group-containing immunogen ABBOTT LABORATORIES (US) 1992-03-31 US disclosed
EP-0399184-A2 Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay ABBOTT LABORATORIES (US) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090285780-A1 PEG LINKER COMPOUNDS AND BIOLOGICALLY ACTIVE CONJUGATES THEREOF MSN, MPEG1, GNE KDM4E 2397/4885KMT2A 3934/4885MEN1 1267/4885
US-20160176924-A1 MODIFIED PEPTIDES AS POTENT INHIBITORS OF THE PSD-95/NMDA RECEPTOR INTERACTION PSD, GRIN1, GRIN3B KDM4E 382/4885KMT2A 365/4885MEN1 1391/4885
US-20210347821-A1 INHIBITORS OF PICK1 AND USES THEREOF DRG1, OPRL1, GAB1 KDM4E 3624/4885KMT2A 2727/4885MEN1 4268/4885
US-20250215052-A1 INHIBITORS OF PICK1 AND USES THEREOF DRG1, PSD, DAB2IP KDM4E 3532/4885KMT2A 2718/4885MEN1 4428/4885
US-20240245793-A1 PSD-95 INHIBITORS AND USES THEREOF PSD, PDLIM5, HDLBP KDM4E 3238/4885KMT2A 3279/4885MEN1 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.