Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22639905 | 0.95 | SIGMAR1 (0.61) | KDM4EALDH1A1CACNA1GSIGMAR1HTR7 | |
| SCHEMBL10899496 | 0.84 | CACNA1G (0.54) | KDM4EALDH1A1CACNA1GSIGMAR1HTR7 | |
| SCHEMBL6776140 | 0.83 | CHKA (0.55) | KDM4EALDH1A1CACNA1GHTR7DRD2 | |
| SCHEMBL2115134 | 0.82 | KMT2A (0.69) | ALDH1A1SIGMAR1HTR7KMT2AHTR1A | |
| SCHEMBL8458456 | 0.82 | CCR2 (0.65) | CCR2 | |
| SCHEMBL10685802 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1CACNA1GSIGMAR1HTR7 | |
| SCHEMBL10689422 | 0.80 | HTR7 (0.74) | CACNA1GHTR7DRD2DRD4FAAH | |
| SCHEMBL23851111 | 0.80 | ALDH1A1 (0.87) | KDM4EALDH1A1SIGMAR1HRH3KMT2A | |
| Hydrochloric Acid SCHEMBL10502937 | 0.79 | KDM4E (0.67) | KDM4EALDH1A1CACNA1GSIGMAR1HTR7 | |
| SCHEMBL8745021 | 0.79 | SIGMAR1 (0.65) | KDM4EALDH1A1SIGMAR1DRD4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686353-B1 | PREVENTING BLOOD MONOCYTES AND LYMPHOCYTES FROM INFILTRATING TISSUE | TEIJIN INTELLECTUAL PROPERTY CENTER LIMITED (JP) | 2004-02-03 | — | — | US | disclosed |
| WO-1997044329-A9 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | — | 1998-03-12 | — | — | WO | disclosed |