SCHEMBL678974

SCHEMBL678974

OCC1C2CC3CC(C2)CC1C3

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.50
CYP2C9 P11712 1/20 0.45
EPHX2 P34913 3/20 0.35
GBA1 P04062 2/20 0.33
UGCG Q16739 2/20 0.33
GBA2 Q9HCG7 2/20 0.33
TDP1 Q9NUW8 1/20 0.32
CXCR3 P49682 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21048748 1.00 HSD11B1 (0.50) HSD11B1CYP2C9EPHX2GBA1UGCG
SCHEMBL16567928 1.00 HSD11B1 (0.50) HSD11B1CYP2C9EPHX2GBA1UGCG
SCHEMBL21426648 0.82 HSD11B1 (0.37) HSD11B1CYP2C9GBA1UGCGGBA2
SCHEMBL8057669 0.82 HSD11B1 (0.38) HSD11B1CYP2C9EPHX2GBA1UGCG
SCHEMBL22642716 0.80 HSD11B1 (0.39) HSD11B1CYP2C9
SCHEMBL2747594 0.77 HSD11B1 (0.46) HSD11B1CYP2C9EPHX2
SCHEMBL3318288 0.71
SCHEMBL13398605 0.71
SCHEMBL1066102 0.69
SCHEMBL1924918 0.69 HSD11B1 (0.61) HSD11B1CYP2C9EPHX2CXCR3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013111158-A2 PROCESS FOR THE PREPARATION OF DPP-IV INHIBITOR MSN LABORATORIES LIMITED (IN) 2013-08-01 WO claimed
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS BRISTOL MYERS SQUIBB CO (US) 2026-05-21 US disclosed
US-12492217-B2 Reagents and their use for modular enantiodivergent synthesis of C—P bonds BRISTOL-MYERS SQUIBB COMPANY (US) 2025-12-09 US disclosed
US-20240285611-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC. (US) 2024-08-29 US disclosed
US-11786519-B2 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases ABBVIE INC. (US) 2023-10-17 US disclosed
US-11759462-B2 Spirocyclic compounds as tryptophan hydroxylase inhibitors ALTAVANT SCIENCES GMBH 2023-09-19 US disclosed
US-20230212204-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS THE SCRIPPS RESEARCH INSTITUTE 2023-07-06 US disclosed
EP-4090664-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS Bristol-Myers Squibb Company (US) 2022-11-23 EP disclosed
CN-115244061-A Reagents and their use for modular enantioselective synthesis of C-P bonds 百时美施贵宝公司 2022-10-25 CN disclosed
US-20210228565-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC. (US) 2021-07-29 US disclosed
US-7402712-B2 Adamantyl vinyl ether compound and production process for the same IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2008-07-22 US disclosed
WO-2008073623-A2 SOLUBLE EPOXIDE HYDROLASE INHIBITORS ARETE THERAPEUTICS, INC. (US) 2008-06-19 WO disclosed
US-20070015793-A1 Synthesis of nojirimycins MACROZYME DNM B.V. (NL) 2007-01-18 US disclosed
US-20070015026-A1 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. 2007-01-18 US disclosed
WO-2005063706-A1 SYNTHESIS OF NOJIRIMYCINS MACROZYME DNM B.V. (NL) 2005-07-14 WO disclosed
US-20050004391-A1 Adamantyl vinyl ether compound and production process for the same IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2005-01-06 US disclosed
EP-1486480-A1 Adamantyl vinyl ether compound and production process for the same Idemitsu Petrochemical Co., Ltd. (JP) 2004-12-15 EP disclosed
US-6238842-B1 SUITABLE FOR USE WITH AN EXPOSURE LIGHT HAVING A WAVELENGTH OF 250 NM OR SHORTER, ESPECIALLY 220 NM OR SHORTER; ACID GENERATING COMPOUND; RESIN HAVING MONOVALENT POLYALICYCLIC GROUPS FUJI PHOTO FILM CO., LTD. (JP) 2001-05-29 US disclosed
US-4739078-A Use of borohydride-salt lanthanide salt reagents for stereo selective reduction of C-15-keto prostaglandin precursors THE UPJOHN COMPANY (US) 1988-04-19 US disclosed
EP-0219580-A1 Stereo-selective reduction THE UPJOHN COMPANY (US) 1987-04-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004391-A1 Adamantyl vinyl ether compound and production process for the same NOTUM, CYP4A11, CYP4F11 HSD11B1 74/4885CYP2C9 214/4885EPHX2 533/4885
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS RNGTT, CDA, DCTD HSD11B1 2238/4885CYP2C9 2179/4885EPHX2 1260/4885
US-20070015793-A1 Synthesis of nojirimycins DHPS, NOS1, MRM1 HSD11B1 1900/4885CYP2C9 439/4885EPHX2 3379/4885
US-20210228565-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES BAX, BCL2, BCL3 HSD11B1 4136/4885CYP2C9 4859/4885EPHX2 3912/4885
US-11759462-B2 Spirocyclic compounds as tryptophan hydroxylase inhibitors TPH1, TPH2, HTR1A HSD11B1 43/4885CYP2C9 196/4885EPHX2 1296/4885
US-20240285611-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES BAX, BCL2, BCL3 HSD11B1 4136/4885CYP2C9 4859/4885EPHX2 3912/4885
US-20230212204-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS PNKP, POLL, RNGTT HSD11B1 3436/4885CYP2C9 1768/4885EPHX2 271/4885
US-11786519-B2 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases BAX, BCL2, BCL3 HSD11B1 4136/4885CYP2C9 4859/4885EPHX2 3912/4885
US-12492217-B2 Reagents and their use for modular enantiodivergent synthesis of C—P bonds PNKP, POLL, RNGTT HSD11B1 3450/4885CYP2C9 1804/4885EPHX2 293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.