Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47864 | 0.89 | KMT2A (0.60) | KMT2AL3MBTL1LMNAGFERSMN1; SMN2 | |
| SCHEMBL10993100 | 0.89 | KMT2A (0.60) | KMT2AL3MBTL1LMNAGFERSMN1; SMN2 | |
| SCHEMBL47874 | 0.86 | KMT2A (0.57) | KMT2AL3MBTL1LMNAGFERSMN1; SMN2 | |
| SCHEMBL13990698 | 0.83 | ALDH1A1 (0.42) | KMT2AL3MBTL1LMNAGFERSMN1; SMN2 | |
| SCHEMBL257610 | 0.82 | KMT2A (0.55) | KMT2AL3MBTL1LMNAGFERSMN1; SMN2 | |
| SCHEMBL10984775 | 0.82 | KMT2A (0.55) | KMT2AL3MBTL1LMNAGFERSMN1; SMN2 | |
| SCHEMBL10990207 | 0.82 | KMT2A (0.55) | KMT2AL3MBTL1LMNAGFERSMN1; SMN2 | |
| SCHEMBL10259158 | 0.82 | SMN1; SMN2 (0.62) | KMT2AL3MBTL1LMNAGFERSMN1; SMN2 | |
| SCHEMBL4454151 | 0.80 | LTA4H (0.55) | KMT2AL3MBTL1LMNAGFERSMN1; SMN2 | |
| SCHEMBL10007534 | 0.80 | LTA4H (0.55) | KMT2AL3MBTL1LMNAGFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097487-A1 | Aromatic sulfonyl alpha-cycloamino hydroxamic acid compounds | G.D. SEARLE & CO. | 2004-05-20 | — | — | US | disclosed |
| US-6638952-B1 | Matrix metalloprotease inhibitors | PHARMACIA CORPORATION | 2003-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097487-A1 | Aromatic sulfonyl alpha-cycloamino hydroxamic acid compounds | MMP1, MMP2, MMP10 | KMT2A 1233/4885L3MBTL1 2579/4885LMNA 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.