SCHEMBL679306

SCHEMBL679306

CCN(CC)CC.COc1c(Cl)ccc(-c2cc(N)c(Cl)c(C(=O)O)n2)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEP1B Q16820 1/20 0.38
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HTR3A P46098 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
HTR4 Q13639 2/20 0.35
TSHR P16473 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KMO O15229 1/20 0.34
HTR2C P28335 2/20 0.34
KCNH2 Q12809 2/20 0.34
HTR3E A5X5Y0 1/20 0.34
SLC22A1 O15245 1/20 0.34
HTR3B O95264 1/20 0.34
LMNA P02545 1/20 0.34
MPO P05164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL115379 0.93 ALDH1A1 (0.40) MEP1BALDH1A1KDM4EHSD17B10TSHR
SCHEMBL29405327 0.93 ALDH1A1 (0.40) MEP1BALDH1A1KDM4EHSD17B10TSHR
SCHEMBL29349463 0.93 ALDH1A1 (0.40) MEP1BALDH1A1KDM4EHSD17B10TSHR
Potassium SCHEMBL679681 0.92 ALDH1A1 (0.40) MEP1BALDH1A1KDM4EHSD17B10TSHR
SCHEMBL679679 0.92 ALDH1A1 (0.40) MEP1BALDH1A1KDM4EHSD17B10TSHR
SCHEMBL2463882 0.85 ALOX5AP (0.39) KDM4ESMN1; SMN2KMOLMNAALOX5AP
SCHEMBL16047307 0.85 KMO (0.40) ALDH1A1KDM4EHSD17B10CYP3A4KMO
SCHEMBL694541 0.85 ALDH1A1 (0.43) ALDH1A1KDM4EHSD17B10TSHRCYP3A4
SCHEMBL29850798 0.84 KMO (0.35) ALDH1A1KDM4EHSD17B10KMOALOX5AP
SCHEMBL15081188 0.84 MEP1B (0.36) MEP1BALDH1A1KDM4EHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2361014-B1 SAFENING 6-(TRISUBSTITUTED PHENYL)-4-AMINO-2-PYRIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS DOW AGROSCIENCES LLC (US) 2017-12-20 EP claimed
EP-2514314-B1 Synergistic herbicidal composition containing certain pyridine carboxylic acids and certain cereal and rice herbicides DOW AGROSCIENCES LLC (US) 2016-06-15 EP claimed
US-9253985-B2 Herbicidal composition for tolerant or resistant cereal crops BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-02-09 US claimed
EP-2926661-A1 Synergistic herbicidal composition containing certain pyridine carboxylic acids and certain cereal and rice herbicides Dow AgroSciences LLC (US) 2015-10-07 EP claimed
EP-2514312-B1 Synergistic herbicidal composition containing certain pyridine or pyrimidine carboxylic acids and certain cereal and rice herbicides DOW AGROSCIENCES LLC (US) 2015-07-08 EP claimed
US-20150175543-A1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES DOW AGROSCIENCES LLC 2015-06-25 US claimed
US-20150126367-A1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES DOW AGROSCIENCES LLC 2015-05-07 US claimed
US-8785350-B2 Herbicidal compositions for tolerant or resistant soybean crops BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-07-22 US claimed
EP-2180790-B1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES DOW AGROSCIENCES LLC (US) 2013-11-20 EP claimed
US-20130023413-A1 HERBICIDAL COMPOSITIONS FOR TOLERANT OR RESISTANT SOYBEAN CROPS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-01-24 US claimed
US-20110294663-A1 Herbicidal composition for tolerant or resistant corn crops BAYER CROPSCIENCE AG (DE) 2011-12-01 US claimed
US-20110287933-A1 Herbicidal composition for tolerant or resistant oilseed rape crops BAYER CROPSCIENCE AG (DE) 2011-11-24 US claimed
US-20110287932-A1 HERBICIDAL COMPOSITION FOR TOLERANT OR RESISTANT CEREAL CROPS BAYER CROPSCIENCE AG (DE) 2011-11-24 US claimed
US-20110287934-A1 HERBICIDAL COMPOSITION FOR TOLERANT OR RESISTANT RICE CROPS BAYER CROPSCIENCE AG (DE) 2011-11-24 US claimed
EP-2361014-B1 SAFENING 6-(TRISUBSTITUTED PHENYL)-4-AMINO-2-PYRIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS DOW AGROSCIENCES LLC (US) 2017-12-20 EP disclosed
US-9253985-B2 Herbicidal composition for tolerant or resistant cereal crops BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-02-09 US disclosed
US-8785350-B2 Herbicidal compositions for tolerant or resistant soybean crops BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-07-22 US disclosed
US-20110287933-A1 Herbicidal composition for tolerant or resistant oilseed rape crops BAYER CROPSCIENCE AG (DE) 2011-11-24 US disclosed
US-20110287932-A1 HERBICIDAL COMPOSITION FOR TOLERANT OR RESISTANT CEREAL CROPS BAYER CROPSCIENCE AG (DE) 2011-11-24 US disclosed
US-20110287934-A1 HERBICIDAL COMPOSITION FOR TOLERANT OR RESISTANT RICE CROPS BAYER CROPSCIENCE AG (DE) 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110287932-A1 HERBICIDAL COMPOSITION FOR TOLERANT OR RESISTANT CEREAL CROPS CYP8B1, HDHD5, HAGH MEP1B 2022/4885ALDH1A1 517/4885KDM4E 2638/4885
US-20110294663-A1 Herbicidal composition for tolerant or resistant corn crops CRY1, CYP8B1, CNPY2 MEP1B 1903/4885ALDH1A1 538/4885KDM4E 2437/4885
US-20150175543-A1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES DHFR, DPYD, DDT MEP1B 3531/4885ALDH1A1 384/4885KDM4E 1949/4885
US-20110287933-A1 Herbicidal composition for tolerant or resistant oilseed rape crops CYP8B1, HDHD5, NCEH1 MEP1B 1827/4885ALDH1A1 648/4885KDM4E 2292/4885
US-20110287934-A1 HERBICIDAL COMPOSITION FOR TOLERANT OR RESISTANT RICE CROPS CYP8B1, DDT, HDHD5 MEP1B 2191/4885ALDH1A1 450/4885KDM4E 2418/4885
US-20130023413-A1 HERBICIDAL COMPOSITIONS FOR TOLERANT OR RESISTANT SOYBEAN CROPS CTH, GGH, CBR3 MEP1B 2603/4885ALDH1A1 798/4885KDM4E 2699/4885
US-20150126367-A1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES DHFR, DPYD, DDT MEP1B 3531/4885ALDH1A1 384/4885KDM4E 1949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.