Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29975451 | 1.00 | KDM4E (0.39) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29658219 | 0.79 | KDM4E (0.40) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5555424 | 0.78 | GPR84 (0.41) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7984547 | 0.75 | HSD17B10 (0.55) | KDM4EMAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL29648165 | 0.74 | IDO1 (0.53) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30503415 | 0.74 | PADI4 (0.55) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL888293 | 0.74 | PADI4 (0.55) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27740 | 0.74 | IDO1 (0.53) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9735627 | 0.73 | CYP2D6 (0.45) | KDM4EMEN1KMT2ALMNAPOLB | |
| SCHEMBL9735632 | 0.73 | CYP2D6 (0.41) | KDM4EMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266774-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-30 | — | — | US | disclosed |
| US-6770667-B1 | N-((IMIDAZOLYL)-PHENYL)-FLUORENE-1-CARBOXAMIDE DERIVATIVES; 5-HYDROXYTRYPTAMINE (5-HT) ANTAGONISTS; PSYCHOLOGICAL, NERVOUS SYSTEM, EATING, BRAIN AND SLEEP DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
| US-6673937-B2 | ANALOGS OF DEOXYPREUSSOMERIN, PALMARUMYCIN CPI AND RELATED NAPHTHOQUINONE SPIROKETALS; INHIBIT THIOREDOXIN-THIOREDOXIN REDUCTASE SYSTEM | THE UNIVERSITY OF PITTSBURGH | 2004-01-06 | — | — | US | disclosed |
| EP-1216240-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-20020049221-A1 | Synthesis and methods of use of new antimitotic agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-04-25 | — | — | US | disclosed |
| WO-2001025229-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266774-A1 | Amide compounds | TPH1, HTR1A, HTR5A | KDM4E 2363/4885MAPT 2576/4885MEN1 1936/4885 |
| US-20020049221-A1 | Synthesis and methods of use of new antimitotic agents | TXNRD1, TXNRD3, TXN2 | KDM4E 3855/4885MAPT 4095/4885MEN1 3341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.