SCHEMBL6815980

SCHEMBL6815980

[CH2]CCCCCCC/C=C\C=C\C=C\CCCC

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
ALDH1A1 P00352 2/20 0.54
FASN P49327 1/20 0.47
FAAH O00519 5/20 0.41
TRPV1 Q8NER1 1/20 0.41
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41
KDM4E B2RXH2 1/20 0.40
CNR1 P21554 2/20 0.38
CNR2 P34972 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28730951 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL18035661 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL28731024 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL2857590 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL2857588 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL18300322 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL28730971 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL10718527 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL4211874 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL10718519 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230338267-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT HENKEL AG & CO. KGAA (DE) 2023-10-26 US disclosed
US-20230338255-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR LIGHTENING PRODUCT HENKEL AG & CO. KGAA (DE) 2023-10-26 US disclosed
US-20210022979-A1 AGENT FOR OXIDATIVE LIGHTENING AND BLEACHING OF THE HAIR HENKEL AG & CO. KGAA (DE) 2021-01-28 US disclosed
US-20180362372-A1 METHOD OF MAKING CELLULOSIC PRODUCTS SOLENIS TECHNOLOGIES, L.P. (US) 2018-12-20 US disclosed
US-20180072595-A1 METHOD FOR IMPROVING SOLID-LIQUID SEPARATION IN WASTE WATER PROCESSES OR CONDITIONING POTABLE WATER SOLENIS TECHNOLOGIES, L.P. 2018-03-15 US disclosed
US-20170305849-A1 METHOD FOR PRODUCING ASTAXANTHIN ESTERS BASF SE (DE) 2017-10-26 US disclosed
US-20170190947-A9 BETA-AMINO ESTER GAS HYDRATE INHIBITORS APERGY BMCS ACQUISITION CORP 2017-07-06 US disclosed
EP-2897576-B1 COMPOSITION FOR TREATING KERATINOUS FIBRES, COMPRISING SPECIFIC AMINOSILICONES, ACIDS AND DIRECT DYES HENKEL AG & CO KGAA (DE) 2017-03-01 EP disclosed
US-20160362595-A1 BETA-AMINO ESTER GAS HYDRATE INHIBITORS NALCO CO (US) 2016-12-15 US disclosed
US-9504639-B2 Composition for treating keratinous fibres, comprising specific aminosilicones, acids and direct dyes HENKEL AG & CO. KGAA (DE) 2016-11-29 US disclosed
US-20150182441-A1 COMPOSITION FOR TREATING KERATINOUS FIBRES, COMPRISING SPECIFIC AMINOSILICONES, ACIDS AND DIRECT DYES HENKEL AG & CO. KGAA (DE) 2015-07-02 US disclosed
US-20140246377-A1 COMPOSITION COMPRISING A NON-IONIC SURFACTANT AND AN IONIC POLYMER ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2014-09-04 US disclosed
EP-2559456-A2 Agent for treating and/or dying ceratinic fibres containing specific aminosilicones and alkalising agent Henkel AG & Co. KGaA (DE) 2013-02-20 EP disclosed
EP-0475160-B2 Preparation for drug application in minute droplet form IDEA AG (DE) 2004-07-14 EP disclosed
EP-0475160-B1 Preparation for drug application in minute droplet form IDEA AG (DE) 1996-02-14 EP disclosed
EP-0475160-A1 Preparation for drug application in minute droplet form Cevc, Gregor, Prof. Dr. (DE) 1992-03-18 EP disclosed
EP-0088046-B1 LIPIDS IN THE AQUEOUS PHASE CIBA-GEIGY AG (CH) 1987-12-09 EP disclosed
US-4619794-A Spontaneous preparation of small unilamellar liposomes CIBA-GEIGY CORPORATION (US) 1986-10-28 US disclosed
EP-0102324-A2 Lipids and surfactants in an aqueous medium CIBA-GEIGY AG (CH) 1984-03-07 EP disclosed
EP-0088046-A2 Lipids in the aqueous phase CIBA-GEIGY AG (CH) 1983-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210022979-A1 AGENT FOR OXIDATIVE LIGHTENING AND BLEACHING OF THE HAIR HAO2, GPX4, ACOX1 TSHR 4584/4885ALDH1A1 50/4885FASN 89/4885
US-20160362595-A1 BETA-AMINO ESTER GAS HYDRATE INHIBITORS SLC43A1, AQP1, SLC6A12 TSHR 4331/4885ALDH1A1 3092/4885FASN 535/4885
US-20170305849-A1 METHOD FOR PRODUCING ASTAXANTHIN ESTERS FASN, ELOVL3, SCD TSHR 1665/4885ALDH1A1 1160/4885FASN 1/4885
US-20230338267-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT OGG1, ALPG, OAT TSHR 3764/4885ALDH1A1 1913/4885FASN 3585/4885
US-20230338255-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR LIGHTENING PRODUCT OGG1, COL14A1, COLGALT1 TSHR 3963/4885ALDH1A1 1323/4885FASN 3512/4885
US-20170190947-A9 BETA-AMINO ESTER GAS HYDRATE INHIBITORS SLC43A1, AQP1, SLC6A12 TSHR 4331/4885ALDH1A1 3092/4885FASN 535/4885
US-20150182441-A1 COMPOSITION FOR TREATING KERATINOUS FIBRES, COMPRISING SPECIFIC AMINOSILICONES, ACIDS AND DIRECT DYES KRT18, TUBB3, TUBB1 TSHR 4698/4885ALDH1A1 957/4885FASN 546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.