Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818426 | 0.88 | KMT2A (0.56) | KCNMA1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6821342 | 0.88 | KCNMA1 (0.56) | KCNMA1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6821049 | 0.84 | MAPT (0.59) | KCNMA1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6818333 | 0.81 | NPC1 (0.69) | MEN1KMT2ASMN1; SMN2PABPC1DUSP3 | |
| SCHEMBL6818334 | 0.80 | ALDH1A1 (0.52) | KCNMA1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6818637 | 0.79 | RAB9A (0.47) | MEN1KMT2AGAASMN1; SMN2PABPC1 | |
| SCHEMBL6824666 | 0.79 | MAPT (0.56) | KCNMA1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL25433021 | 0.75 | RORC (0.60) | KCNMA1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5834919 | 0.74 | MEN1 (0.63) | KCNMA1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6818294 | 0.74 | RAB9A (0.53) | MEN1KMT2AGAASMN1; SMN2PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |