Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | LYN | P07948 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824666 | 0.92 | MAPT (0.56) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL6821342 | 0.88 | KCNMA1 (0.56) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL6822188 | 0.88 | KCNMA1 (0.51) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL6821049 | 0.84 | MAPT (0.59) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL28454501 | 0.81 | KMT2A (0.73) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL6818333 | 0.81 | NPC1 (0.69) | KMT2AMEN1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL6818334 | 0.80 | ALDH1A1 (0.52) | KMT2AMEN1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL25394310 | 0.75 | MAPT (0.71) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL6818294 | 0.74 | RAB9A (0.53) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL8877997 | 0.73 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |