SCHEMBL6833100

SCHEMBL6833100

Cc1ccc(N(C)C(=CC2(N(C)c3ccc(C)cc3)OC(=O)c3ccccc32)N(C)c2ccc(C)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.36
NPSR1 Q6W5P4 5/20 0.36
MAPT P10636 7/20 0.34
POLB P06746 2/20 0.34
GPR55 Q9Y2T6 2/20 0.34
ALOX12 P18054 1/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
TDP1 Q9NUW8 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
GPBAR1 Q8TDU6 1/20 0.34
CES1 P23141 1/20 0.33
CYP3A4 P08684 3/20 0.33
TP53 P04637 2/20 0.33
ALOX15 P16050 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ESR1 P03372 1/20 0.33
TYMS P04818 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6833063 0.87 ALDH1A1 (0.46) MEN1KMT2ATDP1CYP3A4ALDH1A1
SCHEMBL6829601 0.74 NPSR1 (0.43) LMNANPSR1MAPTPOLBGPR55
SCHEMBL822834 0.62 CFTR (0.73) LMNANPSR1MAPTPOLBGPR55
SCHEMBL1618496 0.62 HPGD (0.43) LMNANPSR1MAPTGPR55MEN1
SCHEMBL7850945 0.61 NPSR1 (0.50) LMNANPSR1MAPTPOLBGPR55
SCHEMBL6834819 0.61 ALDH1A1 (0.56) LMNANPSR1MAPTPOLBGPR55
SCHEMBL4577226 0.61 CFTR (0.50) LMNANPSR1MAPTPOLBGPR55
SCHEMBL13869867 0.60 LMNA (0.60) LMNANPSR1MAPTPOLBGPR55
SCHEMBL12715937 0.60 LMNA (0.85) LMNANPSR1MAPTPOLBGPR55
SCHEMBL6832708 0.59 ALDH1A1 (0.44) LMNANPSR1MAPTPOLBGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747170-B2 LEUCO DYES; MOLECULE HAVING AT LEAST TWO AROMATIC RINGS, TWO CARBOXYL GROUPS, AND EITHER TWO AMIDES OR TWO ESTERS; PRESERVATION STABILITY RICOH COMPANY, LTD. (JP) 2004-06-08 US disclosed
US-20040071187-A1 Thermosensitive recording material and color developer compound therefor HAYAKAWA KUNIO (JP) 2004-04-15 US disclosed
US-6555705-B1 A supported thermosensitive recording layer containing a leuco dye and a color developer to induce color in the leuco dye upon heating; using 4-(2- or 4-phenoxyethoxy- or butoxy phthalic acid; image stability; oil, fat repellant RICOH COMPANY, LTD. (JP) 2003-04-29 US disclosed
US-6180560-B1 LEUCO DYE AND DYE DEVELOPER OF AROMATIC AMIDE OR ESTER; PRESERVATION STABILITY RICOH COMPANY, LTD. (JP) 2001-01-30 US disclosed
EP-0612628-B1 Thermosensitive recording material using phthalic acid derivatives RICOH KK (JP) 1996-07-10 EP disclosed
US-5482912-A DEVELOPERS, THERMAL PRINTING, INTERMEDIATE LAYER OF THERMOPLASTIC HOLLOW SPHERES RICOH COMPANY, LTD. (JP) 1996-01-09 US disclosed
EP-0612628-A1 Thermosensitive recording material using phthalic acid derivatives Ricoh Company, Ltd (JP) 1994-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040071187-A1 Thermosensitive recording material and color developer compound therefor LRBA, THEM6, GOT1 LMNA 2817/4885NPSR1 2751/4885MAPT 1317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.