Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.60 |
| ▸ | MME | P08473 | 5/20 | 0.56 |
| ▸ | ACE | P12821 | 4/20 | 0.56 |
| ▸ | CPA1 | P15085 | 2/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020366 | 0.86 | MME (0.55) | EPHX1MMEACECPA1ACE2 | |
| SCHEMBL6841112 | 0.85 | FAAH (0.65) | MMEACECPA1ACE2LMNA | |
| SCHEMBL4585419 | 0.82 | FOLH1 (0.59) | MMEACECPA1ACE2LMNA | |
| SCHEMBL6121330 | 0.81 | LMNA (0.74) | LMNAKMT2AALDH1A1ITGB3ITGAV | |
| SCHEMBL7448015 | 0.81 | ALDH1A1 (0.68) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL22494085 | 0.81 | FAAH (0.65) | LMNAKMT2AKLKB1 | |
| SCHEMBL22494086 | 0.81 | FAAH (0.65) | LMNAKMT2AKLKB1 | |
| SCHEMBL22494084 | 0.81 | FAAH (0.65) | LMNAKMT2AKLKB1 | |
| SCHEMBL6187732 | 0.78 | MME (0.57) | MMEACECPA1ACE2ITGB3 | |
| SCHEMBL6268181 | 0.78 | MME (0.57) | MMEACECPA1ACE2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6767718-B2 | CYCLODEPSIPEPTIDE INTERMEDIATES USED TO SYNTHESIZE NEW LIPODEPSIPEPTIDE ; ANTIBIOTICS; HAVE ANTIBACTERIAL ACTIVITY AGAINST GRAM POSITIVE BACTERIA; LESS TOXIC THAN ANTIBIOTIC DAPTOMYCIN | BIOSOURCE PHARM, INC. | 2004-07-27 | — | — | US | disclosed |
| US-20030224475-A1 | Lipodepsipeptide antibiotics and methods of preparation | BIOSOURCE PHARM, INC. | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224475-A1 | Lipodepsipeptide antibiotics and methods of preparation | NPEPPS, MRPL38, LYPLA2 | EPHX1 4606/4885MME 1372/4885ACE 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.