SCHEMBL685020

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL282005	0.84	FDPS (0.47)	MAPTMEN1KMT2AALDH1A1LMNA
	SCHEMBL4260137	0.82	TRPA1 (0.49)	TRPA1BACE1HDAC3HDAC4HDAC1
	SCHEMBL685658	0.80	TRPA1 (0.41)	TRPA1BACE1HDAC3HDAC4HDAC1
	SCHEMBL685586	0.79	ALDH1A1 (0.44)	TRPA1HDAC3HDAC4HDAC1HDAC7
	SCHEMBL7643558	0.79	TRPA1 (0.42)	TRPA1BACE1HDAC3HDAC4HDAC1
	SCHEMBL685660	0.79	TRPA1 (0.54)	TRPA1MAPTMEN1KMT2AALDH1A1
	SCHEMBL23143191	0.78	MAPT (0.47)	TRPA1BACE1HDAC3HDAC4HDAC1
	SCHEMBL24133302	0.77	LMNA (0.40)	TRPA1MAPTMEN1KMT2ACYP3A4
	SCHEMBL685877	0.76	TRPA1 (0.40)	TRPA1BACE1HDAC3HDAC4HDAC1
	SCHEMBL22864168	0.76	TRPA1 (0.47)	TRPA1BACE1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.