SCHEMBL685594

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL685595	0.84	TSHR (0.47)	PDE4BTSHRMAPK1PDE4APDE4C
	SCHEMBL685757	0.82	PDE4A (0.52)	PDE4BALDH1A1TSHRMAPK1PDE4A
	SCHEMBL685031	0.81	PDE4A (0.35)	PDE4BTSHRMAPK1PDE4APDE4C
	SCHEMBL686119	0.79	TSHR (0.51)	ALDH1A1TSHRMAPK1PKMKMT2A
	SCHEMBL685672	0.79	EGFR (0.37)	PDE4BTSHRMAPK1PDE4APDE4C
	SCHEMBL7642683	0.78	TAS1R3 (0.38)	PDE4BPDE4APDE4CPDE4DEGFR
	SCHEMBL685763	0.78	PTGDR2 (0.42)	TSHRMAPTKMT2AEGFR
	SCHEMBL685900	0.77	SMPD1 (0.49)	PDE4BALDH1A1PRSS1
	SCHEMBL685608	0.76	SMPD1 (0.51)	PDE4BALDH1A1PRSS1
	SCHEMBL685759	0.76	ALDH1A1 (0.38)	PDE4BALDH1A1TSHRMAPTPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.