SCHEMBL685031

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL686114	0.83	EGFR (0.33)	PDE4APDE4BPDE4CPDE4DEGFR
	SCHEMBL685594	0.81	PDE4B (0.39)	PDE4APDE4BPDE4CPDE4DEGFR
	SCHEMBL685757	0.80	PDE4A (0.52)	PDE4APDE4BPDE4CPDE4DTSHR
	SCHEMBL7642683	0.80	TAS1R3 (0.38)	PDE4APDE4BPDE4CPDE4DEGFR
	SCHEMBL685595	0.80	TSHR (0.47)	PDE4APDE4BPDE4CPDE4DTSHR
	SCHEMBL685759	0.77	ALDH1A1 (0.38)	PDE4APDE4BPDE4CPDE4DEGFR
	SCHEMBL685763	0.76	PTGDR2 (0.42)	EGFRXDHTSHRCREBBPCYP3A4
	SCHEMBL685674	0.76	RARA (0.42)	EGFRRXRATHRBMEN1CYP3A4
	SCHEMBL24133302	0.76	LMNA (0.40)	MEN1CYP3A4CYP2C9CYP2C19KMT2A
	SCHEMBL28978485	0.75	THRB (0.44)	EGFRTHRBRORCMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.