SCHEMBL685880

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL685762	0.88	MAPK1 (0.38)	MAPK1HTTEGFRTHRATHRB
	SCHEMBL685674	0.84	RARA (0.42)	LMNAMAPK1HTTEGFRRARA
	SCHEMBL12093586	0.81	PLA2G2D (0.41)	MAPK1HTTEGFRKDM4EALDH1A1
	SCHEMBL686114	0.80	EGFR (0.33)	HTTEGFRKDM4EKMT2ARXRA
	SCHEMBL23120088	0.74	RBP4 (0.45)	LMNAMAPK1HTTPTGDR2SMN1; SMN2
	SCHEMBL29607406	0.74	RBP4 (0.45)	LMNAMAPK1HTTPTGDR2SMN1; SMN2
	SCHEMBL686115	0.74	FYN (0.36)	—
	SCHEMBL1042008	0.72	USP2 (0.44)	LMNAMAPK1HTTEGFRPTGDR2
	SCHEMBL958236	0.72	EGFR (0.48)	LMNAMAPK1HTTEGFRPTGDR2
	SCHEMBL29607317	0.72	EGFR (0.48)	LMNAMAPK1HTTEGFRPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.