SCHEMBL685895

SCHEMBL685895

[C-]#[N+]c1cc(C)c(NC(=O)c2cc(Cn3nnc(C(F)(F)F)n3)nn2-c2ncccc2Cl)c(C(=O)NCC)c1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DHODH Q02127 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL685893 0.93 DHODH (0.32) ALDH1A1SMN1; SMN2DHODH
SCHEMBL685472 0.92 DHODH (0.31) ALDH1A1SMN1; SMN2DHODH
SCHEMBL685631 0.92 SLC2A1 (0.33) ALDH1A1SMN1; SMN2DHODH
SCHEMBL685896 0.92 DHODH (0.32) DHODH
SCHEMBL685911 0.91 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2DHODH
SCHEMBL13084953 0.91 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2DHODH
SCHEMBL13085018 0.91 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2DHODH
SCHEMBL685476 0.90 CRHR1 (0.36)
SCHEMBL13085038 0.90 DHODH (0.35) ALDH1A1SMN1; SMN2DHODH
SCHEMBL13085053 0.90 DHODH (0.33) ALDH1A1SMN1; SMN2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170265470-A1 Anthranilamides in combination with fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-09-21 US disclosed
US-9700049-B2 Anthranilamides in combination with fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-07-11 US disclosed
US-20170156328-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICALCONTROL AGENT BAYER INTELLECTUAL PROPERTY GMBH 2017-06-08 US disclosed
US-9572342-B2 Use of an anthranilic diamide derivatives with heteroaromatic and heterocyclic substituents in combination with a biologicalcontrol agent BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-02-21 US disclosed
US-9414595-B2 Use of anthranilic acid diamide derivatives for pest control in transgenic crops BAYER CROPSCIENCE AG (DE) 2016-08-16 US disclosed
US-20160128331-A1 ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-12 US disclosed
US-9265255-B2 Anthranilamides in combination with fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-02-23 US disclosed
US-20160037775-A1 ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-11 US disclosed
US-9198424-B2 Active ingredient combinations having insecticidal and acaricidal properties BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-01 US disclosed
US-20140364458-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICALCONTROL AGENT BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-12-11 US disclosed
US-20140329676-A1 USE OF ANTHRANILIC ACID DIAMIDE DERIVATIVES FOR PEST CONTROL IN TRANSGENIC CROPS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-11-06 US disclosed
US-8658570-B2 Use of anthranilamide derivatives for controlling insects and spider mites by drenching, soil mixing, furrow treatment, drip application, soil, stem or flower injection, in hydroponic systems, by planting hole treatment or dip application, floating or seedbox application or by treating seed, and also for enhancing the stress tolerance of plants to abiotic stress BAYER CROPSCIENCE AG (DE) 2014-02-25 US disclosed
US-20120022112-A1 USE OF ANTHRANILAMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY DRENCHING, SOIL MIXING, FURROW TREATMENT, DRIP APPLICATION, SOIL, STEM OR FLOWER INJECTION, IN HYDROPONIC SYSTEMS, BY PLANTING HOLE TREATMENT OR DIP APPLICATION, FLOATING OR SEEDBOX APPLICATION OR BY TREATING SEED, AND ALSO FOR ENHANCING THE STRESS TOLERANCE OF PLANTS TO ABIOTIC STRESS BAYER CROPSCIENCE AG (DE) 2012-01-26 US disclosed
US-20120010073-A1 Anthranilamides in combination with fungicides BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2011-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140364458-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICALCONTROL AGENT CYC1, TPD52L2, DBF4 ALDH1A1 2726/4885SMN1; SMN2 3836/4885DHODH 165/4885
US-20120010073-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 ALDH1A1 1960/4885SMN1; SMN2 3895/4885DHODH 815/4885
US-20120022112-A1 USE OF ANTHRANILAMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY DRENCHING, SOIL MIXING, FURROW TREATMENT, DRIP APPLICATION, SOIL, STEM OR FLOWER INJECTION, IN HYDROPONIC SYSTEMS, BY PLANTING HOLE TREATMENT OR DIP APPLICATION, FLOATING OR SEEDBOX APPLICATION OR BY TREATING SEED, AND ALSO FOR ENHANCING THE STRESS TOLERANCE OF PLANTS TO ABIOTIC STRESS CDY1; CDY1B, DHX9, DHX29 ALDH1A1 1757/4885SMN1; SMN2 4769/4885DHODH 265/4885
US-20140329676-A1 USE OF ANTHRANILIC ACID DIAMIDE DERIVATIVES FOR PEST CONTROL IN TRANSGENIC CROPS AADAC, DDT, QDPR ALDH1A1 1661/4885SMN1; SMN2 4329/4885DHODH 235/4885
US-20160128331-A1 ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES AADAC, ANTXR2, CYP51A1 ALDH1A1 1960/4885SMN1; SMN2 3895/4885DHODH 815/4885
US-20170265470-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 ALDH1A1 1960/4885SMN1; SMN2 3895/4885DHODH 815/4885
US-20170156328-A1 USE OF AN ANTHRANILIC DIAMIDE DERIVATIVES WITH HETEROAROMATIC AND HETEROCYCLIC SUBSTITUENTS IN COMBINATION WITH A BIOLOGICALCONTROL AGENT CYC1, TPD52L2, DBF4 ALDH1A1 2726/4885SMN1; SMN2 3836/4885DHODH 165/4885
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties ACHE, ACAT1, ACAT2 ALDH1A1 416/4885SMN1; SMN2 1190/4885DHODH 1758/4885
US-20160037775-A1 ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES ACHE, ACAT1, ACAT2 ALDH1A1 416/4885SMN1; SMN2 1190/4885DHODH 1758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.