Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903470 | 0.82 | CCR1 (0.37) | CCR1CCR5CCR8ALDH1A1 | |
| SCHEMBL6903067 | 0.82 | NPC1 (0.34) | GRM5KDM4ESMN1; SMN2CYP1A2TDP1 | |
| Hydrochloric Acid SCHEMBL6902732 | 0.82 | TRPM8 (0.36) | GRM5TRPM8KDM4ELMNATP53 | |
| SCHEMBL6901129 | 0.79 | SQOR (0.35) | KDM4ELMNATP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL6900038 | 0.79 | HTT (0.34) | KDM4ELMNATP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL6895367 | 0.77 | TGFBR1 (0.38) | GRM5KDM4ELMNATP53SMN1; SMN2 | |
| SCHEMBL6895444 | 0.77 | CYP1A2 (0.34) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL6903610 | 0.76 | PKM (0.40) | GRM5KDM4ELMNATP53SMN1; SMN2 | |
| SCHEMBL6902437 | 0.75 | BRS3 (0.38) | SMN1; SMN2CYP1A2ALDH1A1CYP2D6CYP19A1 | |
| SCHEMBL6901735 | 0.75 | ALDH1A1 (0.33) | LMNASMN1; SMN2L3MBTL1CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |