SCHEMBL6910582

SCHEMBL6910582

CCCCCCCCc1ccc(OS(=O)(=O)[O-])cc1.[Na+]

nearest known ligand 0.72

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 3/20 0.54
THRB known ✓ P10828 2/20 0.49
THRA known ✓ P10827 1/20 0.49
ADORA3 known ✓ P0DMS8 2/20 0.47
PTGS1 known ✓ P23219 1/20 0.47
ADORA2A known ✓ P29274 1/20 0.47
PTGS2 known ✓ P35354 1/20 0.47
CA1 known ✓ P00915 1/20 0.46
FUT7 Q11130 2/20 0.72
STS P08842 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
ESR1 P03372 2/20 0.47
ADRA2A P08913 2/20 0.47
TACR2 P21452 2/20 0.47
SLC6A2 P23975 2/20 0.47
SLC6A4 P31645 2/20 0.47
SLC6A3 Q01959 2/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 2/20 0.47
CYP3A4 P08684 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5320216 1.00 FUT7 (0.72) FUT7CA2STSTHRBTHRA
SCHEMBL5322295 1.00 FUT7 (0.72) FUT7CA2STSTHRBTHRA
SCHEMBL3374603 0.85 CA2 (0.54) FUT7CA2STSTHRBTHRA
SCHEMBL2134736 0.83 CA2 (0.53) FUT7CA2STSTHRBTHRA
SCHEMBL5265636 0.83 CA2 (0.56) FUT7CA2STSTHRBTHRA
Phenol SCHEMBL10936982 0.83 FUT7 (0.51) FUT7CA2STSSMN1; SMN2ESR1
SCHEMBL4062463 0.82 THRB (0.54) FUT7CA2STSTHRBTHRA
SCHEMBL5427923 0.82 CA2 (0.51) FUT7CA2STSTHRBTHRA
SCHEMBL11654904 0.82 THRB (0.54) FUT7CA2STSTHRBTHRA
SCHEMBL29240379 0.82 THRB (0.54) FUT7CA2STSTHRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0971981-B1 EMULSIFIERS FOR AMINO RESINS BASF AG (DE) 2004-10-13 EP disclosed
US-6429252-B1 COMPRISING POLYOXYALKYLENE GLYCOLS, OPTIONALLY ETHERIFIED OR ESTERIFIED; USE AS CURING AGENTS IN AQUEOUS COATING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2002-08-06 US disclosed
US-20020040091-A1 EMULSIFIERS FOR AMINO RESINS BASF AKTIENGESELLSCHAFT (DE) 2002-04-04 US disclosed