Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 5/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047200 | 0.91 | ALDH1A1 (0.54) | CES2CES1ALDH1A1TSHRKIF11 | |
| SCHEMBL28528070 | 0.89 | BCHE (0.46) | CES2CES1ALDH1A1TSHRKIF11 | |
| SCHEMBL6262750 | 0.80 | CES2 (0.48) | CES2CES1ALDH1A1TSHRKIF11 | |
| SCHEMBL63468 | 0.76 | ALDH1A1 (0.67) | CES2CES1ALDH1A1TSHRKIF11 | |
| SCHEMBL1305142 | 0.74 | TSHR (0.48) | ALDH1A1TSHRKIF11SRD5A2CA1 | |
| SCHEMBL7798380 | 0.74 | CES2 (0.46) | CES2ALDH1A1TSHR | |
| SCHEMBL7795640 | 0.72 | CES2 (0.48) | CES2ALDH1A1TSHRMGLLSRD5A2 | |
| SCHEMBL314635 | 0.71 | NPSR1 (0.38) | CES2CES1ALDH1A1KIF11CA1 | |
| SCHEMBL18242051 | 0.70 | TRPV6 (0.48) | CES2CES1ALDH1A1TSHRKIF11 | |
| Iodide SCHEMBL29093539 | 0.70 | ALDH1A1 (0.59) | CES2CES1ALDH1A1TSHRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118996447-A | Phosphine-oxide substituted quinoxaline quinazolinone compound, preparation method and application thereof | 南阳师范学院 | 2024-11-22 | — | — | CN | claimed |
| CN-113457746-B | Catalyst and preparation method and application thereof | 南方科技大学 | 2023-08-22 | — | — | CN | claimed |
| CN-113457746-A | Catalyst and preparation method and application thereof | 南方科技大学 | 2021-10-01 | — | — | CN | claimed |
| CN-109096331-B | Method for preparing o-diaryl phosphoryl substituted phenol derivative | 湖南理工学院 | 2021-10-01 | — | — | CN | claimed |
| CN-118996447-A | Phosphine-oxide substituted quinoxaline quinazolinone compound, preparation method and application thereof | 南阳师范学院 | 2024-11-22 | — | — | CN | disclosed |
| CN-118652272-A | Method for synthesizing thiophosphorus/phosphinic acid ester compound | 中国人民解放军军事科学院防化研究院 | 2024-09-17 | — | — | CN | disclosed |
| US-12012426-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2024-06-18 | — | — | US | disclosed |
| CN-112654630-B | Tetradentate diaminodiphosphine ligands, transition metal complexes, methods for their production and use thereof | 高砂香料工业株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-117659082-A | Method for preparing chlorophosphine based on tetrachlorosilane | 浙江扬帆新材料股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-113457746-B | Catalyst and preparation method and application thereof | 南方科技大学 | 2023-08-22 | — | — | CN | disclosed |
| US-20230219983-A1 | TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2023-07-13 | — | — | US | disclosed |
| CN-116237068-A | Preparation method of 2-phosphonomethyl phenol compound | 广西中烟工业有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| EP-2537839-A1 | B-DIHYDROFURAN DERIVING COMPOUND, METHOD FOR PRODUCING B-DIHYDROFURAN DERIVING COMPOUND OR B-TETRAHYDROFURAN DERIVING COMPOUND, B -GLYCOSIDE COMPOUND, METHOD FOR PRODUCING B-GLYCOSIDE COMPOUND, AND METHOD FOR PRODUCING 4'-ETHYNYL D4T AND ANALOGUE COMPOUNDS THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-20120322995-A1 | beta-DIHYDROFURAN DERIVING COMPOUND, METHOD FOR PRODUCING beta-DIHYDROFURAN DERIVING COMPOUND OR beta-TETRAHYDROFURAN DERIVING COMPOUND, beta-GLYCOSIDE COMPOUND, METHOD FOR PRODUCING beta GLYCOSIDE COMPOUND, AND METHOD FOR PRODUCING 4'-ETHYNYL D4T AND ANALOGUE COMPOUNDS THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-12-20 | — | — | US | disclosed |
| EP-0771812-B1 | Method for producing an optically active diphosphine | TAKASAGO PERFUMERY CO LTD (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-0754696-B1 | Unsymmetric diphosphine monoxide compounds and a process for preparing diphosphine compounds | TAKASAGO PERFUMERY CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-5808162-A | Chiral unsymmetric diphosphine compound and transition metal complex containing the same as ligand | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5693868-A | REACTING 2,2'-BIS(TRIFLUOROMETHANESULFONYLOXY)-1,1-BINAPHTHYL WITH A PHOSPHINE OXIDE IN THE PRESENCE OF A TRANSITION METAL-PHOSPHINE COMPLEX | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0771812-A1 | Method for producing an optically active diphosphine | Takasago International Corporation (JP) | 1997-05-07 | — | — | EP | disclosed |
| EP-0754696-A1 | Chiral unsymmetric diphosphine compounds and transition metal complexes containing them as ligands | Takasago International Corporation (JP) | 1997-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219983-A1 | TETRADENTATE DIAMINODIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX, AND METHOD FOR MANUFACTURING SAME AND APPLICATION FOR SAME | ADH4, ADH5, PF4 | CES2 2676/4885CES1 3668/4885ALDH1A1 219/4885 |
| US-12012426-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | ADH4, ADH5, PF4 | CES2 2676/4885CES1 3668/4885ALDH1A1 219/4885 |
| US-20120322995-A1 | beta-DIHYDROFURAN DERIVING COMPOUND, METHOD FOR PRODUCING beta-DIHYDROFURAN DERIVING COMPOUND OR beta-TETRAHYDROFURAN DERIVING COMPOUND, beta-GLYCOSIDE COMPOUND, METHOD FOR PRODUCING beta GLYCOSIDE COMPOUND, AND METHOD FOR PRODUCING 4'-ETHYNYL D4T AND ANALOGUE COMPOUNDS THEREOF | DHPS, B4GALT1, STT3A | CES2 720/4885CES1 2066/4885ALDH1A1 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.