SCHEMBL694012

SCHEMBL694012

NC(=O)Nc1ccccc1S(=O)(=O)NC(=O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
PTGES O14684 1/20 0.51
FLT1 P17948 1/20 0.49
FLT4 P35916 1/20 0.49
KDR P35968 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CA1 P00915 6/20 0.47
CA2 P00918 5/20 0.47
HDAC3 O15379 2/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC2 Q92769 2/20 0.46
MAPK1 P28482 1/20 0.46
KAT6A Q92794 1/20 0.43
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
IDO1 P14902 1/20 0.43
ALOX15 P16050 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13921975 0.82 TGM2 (0.45) LMNAMEN1KMT2APTGESFLT1
SCHEMBL27476835 0.81 CA1 (0.47) LMNACA1CA2CA9HPGD
SCHEMBL2471746 0.79 LMNA (0.54) LMNAMEN1KMT2APTGESFLT1
SCHEMBL18092287 0.78 CCR8 (0.50) MEN1KMT2ACA1CA2POLB
SCHEMBL10953014 0.77 HDAC3 (0.71) MEN1KMT2AHDAC3HDAC1HDAC2
SCHEMBL19749350 0.77 MEN1 (0.68) LMNAMEN1KMT2AFLT1FLT4
SCHEMBL6962126 0.77 MDM4 (0.56) MEN1KMT2ACA1CA2HDAC3
SCHEMBL27452993 0.77 MEN1 (0.42) LMNAMEN1KMT2APTGESCA1
SCHEMBL29109030 0.76 FLT1 (0.61) LMNAMEN1KMT2APTGESFLT1
SCHEMBL3637063 0.76 LMNA (0.68) LMNAMEN1KMT2APTGESFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137136-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US claimed
US-20100137138-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US claimed
US-20100137137-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US claimed
US-20240239755-A1 SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-07-18 US disclosed
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP disclosed
EP-4387969-A1 SUBSTITUTED 1,2,4-THIADIAZOLYL NICOTINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-06-26 EP disclosed
EP-4387970-A1 SUBSTITUTED 1,2,4-THIADIAZOLYL NICOTINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-06-26 EP disclosed
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-06-20 US disclosed
EP-4380361-A1 USE OF COMPOSITIONS WITH ETHOFUMESATE AND BIXLOZONE IN WHEAT CROPS Bayer Aktiengesellschaft (DE) 2024-06-12 EP disclosed
US-20240174618-A1 SUBSTITUTED (2-HETEROARYLOXYPHENYL)SULFONATES, SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2024-05-30 US disclosed
WO-2024104643-A1 USE OF ISOTIANIL FOR CONTROLLING PLASMODIOPHORA BRASSICA BAYER AKTIENGESELLSCHAFT (DE) 2024-05-23 WO disclosed
WO-2011107443-A1 USE OF PROPINEB FOR PHYSIOLOGICAL CURATIVE TREATMENT UNDER ZINC DEFICIENCY BAYER CROPSCIENCE AG (DE) 2011-09-09 WO disclosed
US-20110218107-A1 Use of Propineb for Physiological Curative Treatment Under Zinc Deficiency BAYER CROPSCIENCE AG (DE) 2011-09-08 US disclosed
WO-2010121735-A1 USE OF PROPINEB AS BIRD REPELLENT BAYER CROPSCIENCE AG (DE) 2010-10-28 WO disclosed
US-20100273874-A1 USE OF PROPINEB AS BIRD REPELLENT BAYER CROPSCIENCE AG (DE) 2010-10-28 US disclosed
US-20100240536-A1 PYRIMIDIN-4-YLPROPANEDINITRILE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2010-09-23 US disclosed
US-20100137139-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US disclosed
US-20100137136-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US disclosed
US-20100137138-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US disclosed
US-20100137137-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137138-A1 HERBICIDE/SAFENER COMBINATION DDT, GSTO1, GAP43 LMNA 3655/4885MEN1 4051/4885KMT2A 2182/4885
US-20100137136-A1 HERBICIDE/SAFENER COMBINATION DDT, GAP43, CYP2W1 LMNA 3660/4885MEN1 3652/4885KMT2A 1948/4885
US-20240239755-A1 SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES PNPO, WEE1, PDXK LMNA 2689/4885MEN1 4547/4885KMT2A 2299/4885
US-20100137137-A1 HERBICIDE/SAFENER COMBINATION DDT, CYP2W1, GAP43 LMNA 4155/4885MEN1 3489/4885KMT2A 1867/4885
US-20100137139-A1 HERBICIDE/SAFENER COMBINATION CYP2W1, DDT, CBR3 LMNA 2737/4885MEN1 2602/4885KMT2A 1782/4885
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES HPD, DDT, PPOX LMNA 4598/4885MEN1 4729/4885KMT2A 1954/4885
US-20110218107-A1 Use of Propineb for Physiological Curative Treatment Under Zinc Deficiency PLPBP, ZFR, CTRB1 LMNA 4573/4885MEN1 2869/4885KMT2A 2041/4885
US-20240174618-A1 SUBSTITUTED (2-HETEROARYLOXYPHENYL)SULFONATES, SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS STS, GMDS, AGPS LMNA 4676/4885MEN1 4697/4885KMT2A 1657/4885
US-20100273874-A1 USE OF PROPINEB AS BIRD REPELLENT NMBR, EPHB4, EPHB1 LMNA 4337/4885MEN1 1468/4885KMT2A 1600/4885
US-20100240536-A1 PYRIMIDIN-4-YLPROPANEDINITRILE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS DDT, PLPBP, HPD LMNA 3510/4885MEN1 3857/4885KMT2A 2759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.