Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937181 | 0.88 | ADAM17 (0.35) | ALDH1A1GAAOPRK1 | |
| SCHEMBL7937125 | 0.83 | ALDH1A1 (0.31) | TGFBR1ALDH1A1GAASLC6A3 | |
| SCHEMBL6944566 | 0.80 | P2RX3 (0.31) | P2RX3 | |
| SCHEMBL7928806 | 0.79 | P2RX3 (0.34) | P2RX3TGFBR1ALDH1A1GAASLC6A3 | |
| SCHEMBL6986001 | 0.79 | MASP2 (0.32) | P2RX3TGFBR1 | |
| SCHEMBL7930219 | 0.79 | TGFBR1 (0.31) | P2RX3TGFBR1 | |
| SCHEMBL6988069 | 0.78 | MASP2 (0.32) | P2RX3TGFBR1 | |
| SCHEMBL6948116 | 0.77 | TGFBR1 (0.32) | P2RX3TGFBR1 | |
| SCHEMBL8112771 | 0.77 | SLC6A3 (0.31) | P2RX3TGFBR1SLC6A3 | |
| SCHEMBL6942474 | 0.77 | P2RX3 (0.33) | P2RX3TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235787-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-05-22 | — | — | US | disclosed |