Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986981 | 0.89 | MCL1 (0.40) | MEN1ALDH1A1KMT2AFPR1FPR2 | |
| SCHEMBL6983751 | 0.85 | NR3C1 (0.40) | MAPTMEN1ALDH1A1KMT2AFPR1 | |
| SCHEMBL6980994 | 0.84 | RXRA (0.43) | MAPTMEN1ALDH1A1KMT2ATP53 | |
| SCHEMBL6985290 | 0.82 | ALDH1A1 (0.58) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL6985566 | 0.81 | PARP14 (0.40) | MAPTMEN1ALDH1A1KMT2ATP53 | |
| SCHEMBL6985322 | 0.81 | GAA (0.41) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL6987632 | 0.80 | ALDH1A1 (0.39) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL6977890 | 0.80 | SLC16A3 (0.46) | MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL6986002 | 0.79 | RXRA (0.45) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL6986817 | 0.79 | THRB (0.42) | MAPTALDH1A1LMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |