Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985749 | 0.91 | ALDH1A1 (0.48) | MAPTMAPK1NR3C1ALDH1A1LMNA | |
| SCHEMBL6985322 | 0.90 | GAA (0.41) | MAPTNPC1RAB9ANR3C1ALDH1A1 | |
| SCHEMBL6982764 | 0.89 | FPR1 (0.43) | SMN1; SMN2MAPTNR3C1ALDH1A1LMNA | |
| SCHEMBL6984759 | 0.89 | LMNA (0.47) | SMN1; SMN2MAPTNR3C1ALDH1A1LMNA | |
| SCHEMBL7408050 | 0.89 | TP53 (0.40) | SMN1; SMN2MAPTNR3C1ALDH1A1LMNA | |
| SCHEMBL6982163 | 0.87 | SLC16A3 (0.45) | SMN1; SMN2MAPTNR3C1ALDH1A1LMNA | |
| SCHEMBL7411038 | 0.86 | PKM (0.43) | SMN1; SMN2MAPTNR3C1ALDH1A1LMNA | |
| SCHEMBL6977498 | 0.85 | CCKBR (0.44) | MAPTNR3C1ALDH1A1LMNAMEN1 | |
| SCHEMBL6984039 | 0.85 | TP53 (0.45) | MAPTNR3C1ALDH1A1LMNAHTT | |
| SCHEMBL6982953 | 0.83 | CCR10 (0.39) | SMN1; SMN2MAPTALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |