Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984039 | 0.89 | TP53 (0.45) | LMNACNR1HTTMAPTALDH1A1 | |
| SCHEMBL6984759 | 0.89 | LMNA (0.47) | LMNAHTTMAPTMEN1ALDH1A1 | |
| SCHEMBL6982953 | 0.86 | CCR10 (0.39) | LMNACNR1HPGDTSHRMAPT | |
| SCHEMBL6985322 | 0.84 | GAA (0.41) | LMNATSHRMAPTMEN1ALDH1A1 | |
| SCHEMBL6978212 | 0.84 | TRIM24 (0.48) | MEN1KMT2ATP53 | |
| SCHEMBL6977498 | 0.84 | CCKBR (0.44) | LMNANPSR1MAPTMEN1ALDH1A1 | |
| SCHEMBL6977890 | 0.84 | SLC16A3 (0.46) | SLC16A3HPGDTSHRMEN1ALDH1A1 | |
| SCHEMBL6982821 | 0.83 | MAPT (0.41) | LMNAHTTNPSR1MAPTMEN1 | |
| SCHEMBL6978202 | 0.82 | ALDH1A1 (0.37) | HPGDTSHRMAPTMEN1ALDH1A1 | |
| SCHEMBL7414191 | 0.82 | PKM (0.42) | NPSR1HPGDTSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |