Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980148 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL6981458 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL6984357 | 0.90 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL7135238 | 0.86 | ADRA1B (0.44) | ALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL6986741 | 0.83 | MTNR1A (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL6985464 | 0.81 | LMNA (0.36) | SMN1; SMN2ALDH1A1HTTKMT2APOLB | |
| SCHEMBL6985684 | 0.81 | ADRA1B (0.47) | L3MBTL1 | |
| SCHEMBL6986641 | 0.78 | EPHX2 (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL6985013 | 0.78 | KMT2A (0.39) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL6987065 | 0.78 | POLB (0.39) | ALDH1A1KMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |