Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994828 | 0.76 | LMNA (0.37) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL27475357 | 0.75 | ALDH1A1 (0.51) | ALDH1A1LMNAL3MBTL1KDM4EHPGD | |
| SCHEMBL6998457 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL6992790 | 0.69 | SIRT1 (0.45) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL27459777 | 0.68 | ADRA2A (0.53) | ALDH1A1LMNAL3MBTL1KDM4EHPGD | |
| SCHEMBL3559889 | 0.67 | GFER (0.44) | ALDH1A1KDM4EHPGDALOX15TSHR | |
| SCHEMBL17221651 | 0.66 | RAB9A (0.44) | PTGS2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2479366 | 0.66 | POLB (0.70) | ALDH1A1LMNAL3MBTL1KDM4EHPGD | |
| SCHEMBL27387994 | 0.65 | ALOX15 (0.51) | ALOX15PTGS2PTGS1TP53GPR17 | |
| SCHEMBL17221460 | 0.65 | GABRA1 (0.36) | KDM4EPTGS2PTGS1GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003724-B1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | AVENTIS PHARMA GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-6114349-A | Substituted quinoline derivatives with antiviral action | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |
| EP-1003724-A1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | Aventis Pharma Deutschland GmbH (DE) | 2000-05-31 | — | — | EP | disclosed |
| WO-1997037977-A1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-16 | — | — | WO | disclosed |