Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 17/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 17/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 17/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 17/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 17/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 17/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 17/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196066 | 0.91 | PRKAB2 (0.38) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL7009049 | 0.81 | ALDH1A1 (0.42) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL6714654 | 0.72 | IDO1 (0.39) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL6295747 | 0.71 | ABCG2 (0.51) | — | |
| SCHEMBL7016620 | 0.70 | KIF11 (0.42) | — | |
| SCHEMBL11203471 | 0.69 | GPR84 (0.38) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL25198348 | 0.69 | CCNT1 (0.45) | — | |
| SCHEMBL25228250 | 0.68 | TUBB4A (0.48) | — | |
| SCHEMBL5716984 | 0.68 | ALOX5 (0.41) | PTGS1PTGS2 | |
| SCHEMBL11204197 | 0.68 | IDO1 (0.38) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313708-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018345-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |