Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4256389 | 0.96 | ALDH1A1 (0.31) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL5967516 | 0.92 | ALDH1A1 (0.39) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| Phosphoric Acid SCHEMBL2830544 | 0.74 | — | — | |
| SCHEMBL15847108 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL10335264 | 0.73 | — | — | |
| SCHEMBL5983979 | 0.71 | CYP2C19 (0.39) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL5034921 | 0.68 | ALDH1A1 (0.37) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL21647263 | 0.68 | ALDH1A1 (0.46) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL9483954 | 0.68 | ALDH1A1 (0.46) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| Citric Acid SCHEMBL4564858 | 0.67 | ALDH1A1 (0.75) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278819-A1 | LIQUID DETERGENT COMPOSITIONS | The Procter & Gamble Company (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001085887-A1 | LIQUID DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2001-11-15 | — | — | WO | disclosed |
| EP-1124929-A1 | BLEACH-CONTAINING DETERGENT COMPOSITION | The Procter & Gamble Company (US) | 2001-08-22 | — | — | EP | disclosed |
| EP-1123376-A2 | LAUNDRY AND CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-1080168-A2 | DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-2000027968-A1 | BLEACH-CONTAINING DETERGENT COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2000-05-18 | — | — | WO | disclosed |
| WO-2000002436-A2 | DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-20 | — | — | WO | disclosed |
| WO-2000002982-A2 | LAUNDRY AND CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-20 | — | — | WO | disclosed |
| EP-0929637-A4 | A DETERGENT COMPOSITION COMPRISING CATIONIC AMINES AND LIPASE ENZYMES | PROCTER & GAMBLE (US) | 2000-01-05 | — | — | EP | disclosed |
| EP-0929637-A1 | A DETERGENT COMPOSITION COMPRISING CATIONIC AMINES AND LIPASE ENZYMES | THE PROCTER & GAMBLE COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013463-A1 | A DETERGENT COMPOSITION COMPRISING CATIONIC AMINES AND LIPASE ENZYMES | THE PROCTER & GAMBLE COMPANY (US) | 1998-04-02 | — | — | WO | disclosed |