Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7033006 | 0.83 | MMP13 (0.42) | CA2KMT2AHTTALDH1A1MEN1 | |
| SCHEMBL4190555 | 0.80 | HTT (0.67) | CA2KMT2AHTTMEN1GAA | |
| SCHEMBL9325260 | 0.79 | CA2 (0.78) | CA2KMT2AHTTALDH1A1MEN1 | |
| SCHEMBL7387548 | 0.78 | ALDH1A1 (0.70) | KMT2AHTTALDH1A1MEN1LMNA | |
| SCHEMBL7033015 | 0.77 | CA2 (0.58) | CA2ALDH1A1LMNALOX | |
| SCHEMBL2879769 | 0.76 | LMNA (0.46) | CA2KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL482310 | 0.75 | PKM (0.58) | HTTALDH1A1LMNAGAANPSR1 | |
| SCHEMBL5484013 | 0.74 | LMNA (0.45) | CA2KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL505791 | 0.74 | ALDH1A1 (0.69) | CA2KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL13551948 | 0.74 | ENPP2 (0.46) | ALDH1A1LMNASMN1; SMN2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841323-B1 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL CO (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6201131-B1 | REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-13 | — | — | US | disclosed |
| US-5902905-A | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0841323-A2 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-05-13 | — | — | EP | disclosed |