Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.32 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523879 | 0.73 | LMNA (0.37) | TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL11588594 | 0.71 | CA1 (0.30) | CA1TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL11588124 | 0.71 | CA2 (0.30) | CA2 | |
| SCHEMBL11589714 | 0.71 | SLC1A3 (0.30) | — | |
| SCHEMBL11591400 | 0.71 | — | — | |
| L-Lactic Acid SCHEMBL9420938 | 0.69 | TP53 (0.40) | CA2CA1TSHRMEN1ALDH1A1 | |
| Potassium Ion SCHEMBL11527857 | 0.68 | LMNA (0.32) | TSHR | |
| L-Lactic Acid SCHEMBL28265393 | 0.67 | TP53 (0.38) | CA2CA1TSHRMEN1ALDH1A1 | |
| L-Lactic Acid SCHEMBL3182661 | 0.67 | TP53 (0.38) | CA2CA1TSHRMEN1ALDH1A1 | |
| Silver SCHEMBL6735440 | 0.67 | CA1 (0.40) | CA2CA1TSHRCYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015428-B1 | SULFO-N-HYDROXY SUCCINIMIDE AND METHOD OF PREPARATION | PIERCE CHEMICAL CO (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6407263-B1 | CHEMICAL INTERMEDIATE FOR SUCCINIMIDE | PIERCE CHEMICAL COMPANY | 2002-06-18 | — | — | US | disclosed |
| EP-1015428-A1 | SULFO-N-HYDROXY SUCCINIMIDE AND METHOD OF PREPARATION | PIERCE CHEMICAL COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| US-5942628-A | Method for the preparation of sulfo-N-hydroxy succinimade salts | PIERCE CHEMICAL COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| US-5892057-A | Preparation of sulfo-N-hydroxysuccinimide salts | PIERCE CHEMICAL COMPANY (US) | 1999-04-06 | — | — | US | disclosed |
| WO-1999014192-A1 | SULFO-N-HYDROXY SUCCINIMIDE AND METHOD OF PREPARATION | PIERCE CHEMICAL COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |