Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516808 | 0.83 | MAPK1 (0.37) | MAPK1CA4ALDH1A1ALOX15 | |
| SCHEMBL704633 | 0.79 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15 | |
| SCHEMBL706107 | 0.77 | CA4 (0.37) | MAPK1CA4ALDH1A1ALOX15LTA4H | |
| SCHEMBL23985417 | 0.76 | MAPK1 (0.32) | MAPK1ALDH1A1ALOX15 | |
| SCHEMBL703370 | 0.76 | MAPK1 (0.32) | MAPK1ALDH1A1ALOX15 | |
| SCHEMBL713132 | 0.76 | RELA (0.33) | MAPK1ALDH1A1ALOX15LTA4H | |
| SCHEMBL705807 | 0.73 | ALDH1A1 (0.37) | ALDH1A1KCNN4 | |
| SCHEMBL705121 | 0.73 | MEN1 (0.35) | MAPK1ALDH1A1LTA4H | |
| SCHEMBL27538454 | 0.70 | CA1 (0.37) | ALDH1A1ALOX15CA1CA2CA9 | |
| SCHEMBL707593 | 0.70 | LTA4H (0.42) | MAPK1ALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070282121-A1 | INTERMEDIATES FOR THE SYNTHESIS OF POLYPROPIONATE ANTIBIOTICS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-12-06 | — | — | US | claimed |
| US-7297807-B1 | Intermediates for the synthesis of polypropionate antibiotics | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2007-11-20 | — | — | US | claimed |
| US-5350846-A | Antibiotics | MERCK & CO., INC. (US) | 1994-09-27 | — | — | US | claimed |
| US-5247074-A | Antibiotics | MERCK & CO., INC. (US) | 1993-09-21 | — | — | US | claimed |
| US-5208329-A | Antibacterial agents | MERCK & CO., INC. (US) | 1993-05-04 | — | — | US | claimed |
| US-5182385-A | Chemical intermediates for bactericides | MERCK & CO., INC. (US) | 1993-01-26 | — | — | US | claimed |
| EP-0465126-A2 | Carbapenem antibacterial agents | MERCK & CO. INC. (US) | 1992-01-08 | — | — | EP | claimed |
| US-12109812-B2 | Ink jet printing method and ink jet printing apparatus | SEIKO EPSON CORPORATION (JP) | 2024-10-08 | — | — | US | disclosed |
| CN-114055975-B | Ink jet recording method and ink jet recording apparatus | 精工爱普生株式会社 | 2023-05-12 | — | — | CN | disclosed |
| EP-4172171-A1 | 3.ALPHA.-HYDROXY, 17.BETA.-C(O)-N-ARYL SUBSTITUTED NEUROACTIVE STEROIDS AND COMPOSITIONS THEREOF | Sage Therapeutics, Inc. (US) | 2023-05-03 | — | — | EP | disclosed |
| US-20230045939-A1 | STABLE VACCINE AGAINST CLOSTRIDIUM DIFFICILE | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-02-16 | — | — | US | disclosed |
| EP-4121072-A1 | CYCLIC SULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | Amathus Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| CN-108588151-B | Process for large scale enzymatic synthesis of oligosaccharides | 台湾地区“中央研究院” | 2022-05-13 | — | — | CN | disclosed |
| US-5350846-A | Antibiotics | MERCK & CO., INC. (US) | 1994-09-27 | — | — | US | disclosed |
| US-5247074-A | Antibiotics | MERCK & CO., INC. (US) | 1993-09-21 | — | — | US | disclosed |
| US-5208329-A | Antibacterial agents | MERCK & CO., INC. (US) | 1993-05-04 | — | — | US | disclosed |
| US-5182385-A | Chemical intermediates for bactericides | MERCK & CO., INC. (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0467434-A1 | 2-Biphenyl-carbapenem antibacterial agents | MERCK & CO. INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0465126-A2 | Carbapenem antibacterial agents | MERCK & CO. INC. (US) | 1992-01-08 | — | — | EP | disclosed |
| EP-0464900-A2 | 2-Biphenyl-carbapenems | MERCK & CO. INC. (US) | 1992-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070282121-A1 | INTERMEDIATES FOR THE SYNTHESIS OF POLYPROPIONATE ANTIBIOTICS | DHPS, EMG1, RPN1 | MAPK1 2600/4885CA4 4411/4885ALDH1A1 2566/4885 |
| US-20230045939-A1 | STABLE VACCINE AGAINST CLOSTRIDIUM DIFFICILE | DDOST, SI, CD4 | MAPK1 4334/4885CA4 1028/4885ALDH1A1 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.