Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAP2 | P11137 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074236 | 0.92 | POLB (0.47) | EGFRCDK2KIF11POLBPKM | |
| SCHEMBL7842628 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1MAPTNPSR1HPGD | |
| SCHEMBL7592453 | 0.72 | GPR35 (0.43) | NPSR1CNR1 | |
| SCHEMBL7682574 | 0.71 | KDM4A (0.43) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL31025881 | 0.70 | ALDH1A1 (0.53) | EGFRCDK2KIF11KMT2AKDM4E | |
| SCHEMBL21392230 | 0.69 | KIF11 (0.50) | EGFRCDK2KIF11KMT2AKDM4E | |
| SCHEMBL7072708 | 0.69 | GPR17 (0.61) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL7680945 | 0.69 | PTPRC (0.44) | ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL9864307 | 0.69 | MAPT (0.65) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL622987 | 0.68 | KMT2A (0.45) | KMT2AKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003504-B1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-07-02 | — | — | EP | disclosed |